Results 191 to 200 of about 52,860 (309)

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, Volume 36, Issue 4, July 2026.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation. [PDF]

Nat Neurosci
Karadas M, Gill JV, Ceballo S, Shoham S, Rinberg D.   +4 more
europepmc   +1 more source

Investigating the Effect of Tumour Necrosis Factor Antagonist on Olfaction

Clinical Otolaryngology, Volume 51, Issue 4, Page 504-511, July 2026.
ABSTRACT Objectives Tumour Necrosis factor antagonists is a potent anti‐inflammatory medication and has shown to improve olfactory function in murine models. The primary aim was to determine the effect of TNF antagonists on olfactory performance in humans.
Andreas Espehana, George Macfarlane, Elizabeth Mairenn Garden, Liam Lee, Gabija Klyvyte, Lavandan Jegatheeswaran, Rebecca Davies, Carl Philpott   +7 more
wiley   +1 more source

Gamma and beta oscillatory signatures of the human olfactory bulb encode odor valence and sampling. [PDF]

iScience
Li S, Mignot C, Weise S, Hummel T.
europepmc   +1 more source

Responses of Fruit Flies (Diptera: Tephritidae) to Protein Bait Applied at Different Densities

Journal of Applied Entomology, Volume 150, Issue 6, Page 736-742, July 2026.
ABSTRACT The effectiveness of odour‐based lures for insects is related to their active space, the air volume around an odour source in which an insect will detect and move towards it. This principle applies to protein baits laced with toxicants that are used as either sprays or stations to suppress pest fruit fly populations.
Msizi R. Ramaoka, Aruna Manrakhan, Christopher W. Weldon   +2 more
wiley   +1 more source

Acetylome Analyses Provide New Insights Into the Effects of Childhood Allergic Rhinitis on Olfactory Bulb-Dependent Olfactory Impairment. [PDF]

Allergy
Wang R, Xu Z, Zhang Y, Wang Q, Li M, Liang J, Zhan X, Lu Y, Yuan J, Wang S, Gu Q.   +10 more
europepmc   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, Volume 600, Issue 12, Page 1699-1716, June 2026.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Comparative Effects of Anti-Inflammatory Therapies on Olfactory Bulb Histopathology and Olfactory Function in a Rat Model of Experimental Allergic Rhinitis. [PDF]

J Inflamm Res
Kayıkçı E, Kayıkçı H.
europepmc   +1 more source

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

Advanced Materials, Volume 38, Issue 33, 12 June 2026.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang, Jiaqi Zhang, Mei Cui, Wei Qi, Renliang Huang, Rongxin Su, Kai Zhang   +6 more
wiley   +1 more source

Stimulating the Human Olfactory Bulb to Evoke Smell Perception: A Case Report from Awake Brain Surgery. [PDF]

ORL J Otorhinolaryngol Relat Spec
Mignot C, Weise S, Sobottka SB, Bensafi M, Podlesek D, Hummel T.   +5 more
europepmc   +1 more source