Brain Insulin Receptor Causes Activity-Dependent Current Suppression in the Olfactory Bulb Through Multiple Phosphorylation of Kv1.3 [PDF]
Debra Ann Fadool+3 more
openalex +1 more source
Pharmacokinetics and pharmacodynamics of intranasal insulin in a rat brain
Abstract Background and Purpose Understanding of the insulin‐mediated effects on signalling and metabolism is important not only for fundamental knowledge of insulin's action in the brain but also for elucidating the mechanism of therapeutic potential in neurodegenerative disorders with underlying brain metabolic dysfunction.
Jelena Osmanovic Barilar+7 more
wiley +1 more source
Clinical significance of MRI-measured olfactory bulb height as an imaging biomarker of idiopathic Parkinson's disease. [PDF]
Park S+6 more
europepmc +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
A. Nunez-Parra+4 more
semanticscholar +1 more source
Abstract INTRODUCTION Plasma‐to‐autopsy studies are essential to understand how tau blood biomarkers change in relation to Alzheimer's disease (AD) brain pathology and how they are influenced by brain co‐pathologies and comorbidities. METHODS Plasma samples from 102 brain donors of the Vallecas Alzheimer Reina Sofia cohort were analyzed using a mass ...
Laia Montoliu‐Gaya+20 more
wiley +1 more source
Gene expression differences in the olfactory bulb associated with differential social interactions and olfactory deficits in Pax6 heterozygous mice. [PDF]
Daems C+4 more
europepmc +1 more source
Dopaminergic Neurons in the Zebrafish Subpallium Belong to the Extended Medial Amygdala
We identify directly adjacent to the pallial–subpallial boundary a pax6a‐negative dorsal Vdd2 portion of the zebrafish larval subpallium that develops into the extended medial amygdala (EMeA). Zebrafish subpallial dopaminergic neurons that locate to Vdd2 belong to the EMeA and form a heterogeneous group differentially expressing calbindin2a and ...
Daniel Armbruster+2 more
wiley +1 more source
Impaired olfactory bulb neurogenesis mediated by Notch1 contributes to olfactory dysfunction in mice chronically exposed to methamphetamine. [PDF]
Gu C+13 more
europepmc +1 more source