Results 261 to 270 of about 243,434 (387)

Pharmacokinetics and pharmacodynamics of intranasal insulin in a rat brain

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 17, Page 4020-4040, September 2025.
Abstract Background and Purpose Understanding of the insulin‐mediated effects on signalling and metabolism is important not only for fundamental knowledge of insulin's action in the brain but also for elucidating the mechanism of therapeutic potential in neurodegenerative disorders with underlying brain metabolic dysfunction.
Jelena Osmanovic Barilar   +7 more
wiley   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Disruption of centrifugal inhibition to olfactory bulb granule cells impairs olfactory discrimination

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
A. Nunez-Parra   +4 more
semanticscholar   +1 more source

Plasma tau biomarkers are distinctly associated with tau tangles and decreased with Lewy body pathology

open access: yesAlzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract INTRODUCTION Plasma‐to‐autopsy studies are essential to understand how tau blood biomarkers change in relation to Alzheimer's disease (AD) brain pathology and how they are influenced by brain co‐pathologies and comorbidities. METHODS Plasma samples from 102 brain donors of the Vallecas Alzheimer Reina Sofia cohort were analyzed using a mass ...
Laia Montoliu‐Gaya   +20 more
wiley   +1 more source

Dopaminergic Neurons in the Zebrafish Subpallium Belong to the Extended Medial Amygdala

open access: yesJournal of Comparative Neurology, Volume 533, Issue 8, August 2025.
We identify directly adjacent to the pallial–subpallial boundary a pax6a‐negative dorsal Vdd2 portion of the zebrafish larval subpallium that develops into the extended medial amygdala (EMeA). Zebrafish subpallial dopaminergic neurons that locate to Vdd2 belong to the EMeA and form a heterogeneous group differentially expressing calbindin2a and ...
Daniel Armbruster   +2 more
wiley   +1 more source

Impaired olfactory bulb neurogenesis mediated by Notch1 contributes to olfactory dysfunction in mice chronically exposed to methamphetamine. [PDF]

open access: yesCell Biol Toxicol
Gu C   +13 more
europepmc   +1 more source

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