Results 191 to 200 of about 52,033 (255)

FMRP‐Mediated Proteasome Regulation: A Novel Mechanism in ALS Pathology

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Schematic model of TDP‐43/TNKS‐mediated proteasome regulation in WT, FMRP‐depleted, and TDP‐43A315T‐Tg ALS neurons. In WT neurons, cytoplasmic TDP‐43 partially sequesters TNKS, maintaining balanced PI31 ribosylation and proteasome activity. FMRP depletion promotes nuclear translocation of TDP‐43, enhances TNKS/PI31 interaction, and increases axonal ...
Pritha Majumder   +5 more
wiley   +1 more source

Time‐ and Region‐Specific Effects of Intranasal Insulin on Oxidative Stress Parameters in the Rat Brain

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Intranasal insulin induced time‐dependent heterogeneous oxidative stress–related responses across brain regions, with opposite patterns in the olfactory and respiratory epithelia, while plasma redox parameters were minimally affected. These redox modulations were found associated with insulin signaling markers, including C‐peptide, AMPK activity, and ...
Jelena Osmanovic Barilar   +8 more
wiley   +1 more source

[Depressive disorders and olfactory dysfunction]. [PDF]

open access: yesZhong Nan Da Xue Xue Bao Yi Xue Ban
Tang Y, Zou L, Chen X, Yan C.
europepmc   +1 more source

Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction. [PDF]

open access: yesInt Forum Allergy Rhinol
Eckert MA   +3 more
europepmc   +1 more source

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