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Nihon rinsho. Japanese journal of clinical medicine, 2019
Patients with Parkinson's disease (PD) are known to suffer from a variety of non-motor symptoms, such as olfactory dysfunction. In fact, the impaired sense of smell is suggested to precede clinically detectable motor signs by several years. Furthermore, several studies demonstrated that the earliest neuropathological changes in PD brain appeared in the
Sayaka, Taniguchi, Atsushi, Takeda
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Patients with Parkinson's disease (PD) are known to suffer from a variety of non-motor symptoms, such as olfactory dysfunction. In fact, the impaired sense of smell is suggested to precede clinically detectable motor signs by several years. Furthermore, several studies demonstrated that the earliest neuropathological changes in PD brain appeared in the
Sayaka, Taniguchi, Atsushi, Takeda
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Characterization of Olfactory Dysfunction
Archives of Otolaryngology - Head and Neck Surgery, 1987Management of dysosmic patients frequently is hampered by an incomplete description of their chief complaint and sometimes inadequate qualitative analysis of their symptoms. Qualitative analysis of olfactory dysfunction by an Odorant Confusion Matrix helps to characterize more fully sense of smell in the dysosmic patient.
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Olfactory dysfunction in multiple sclerosis
Multiple Sclerosis and Related Disorders, 2018Multiple sclerosis (MS) is a common chronic neurological disease that causes disability. MS can have various clinical manifestations, one of which is olfactory dysfunction. In clinical practice, olfactory disturbances are usually underdiagnosed.
Arife Çimen, Atalar +5 more
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Olfactory Dysfunction in Parkinson’s Disease
ORL, 1991An olfactory function test in 18 patients with Parkinson's disease (PD) and 10 age-matched control subjects was performed. Both detection and recognition thresholds were measured with five kinds of synthesized odorants (T & T olfactometry). Before each test, rhinoscopic inspections were performed to exclude subjects who could have respiratory hyposmia.
T, Murofushi +3 more
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Olfactory Dysfunction in Neurodegenerative Diseases
Current Allergy and Asthma Reports, 2018The sense of smell is today one of the focuses of interest in aging and neurodegenerative disease research. In several neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease, the olfactory dysfunction is one of the initial symptoms appearing years before motor symptoms and cognitive decline, being considered a clinical marker ...
Concepció, Marin +7 more
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Olfactory dysfunctions in neurodegenerative disorders
Journal of Neuroscience Research, 2012AbstractOlfactory dysfunction is a common symptom in the patients with neurodegenerative disorders, particularly in Parkinson's disease (PD) and Alzheimer's disease (AD). Recently, studies of olfactory dysfunction have focused on its potential as a medication‐independent biomarker for disease progression and as an early indicator for the diagnosis of ...
Yang, Ruan +4 more
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Olfactory dysfunction following herpetic meningoencephalitis
Journal of Neurology, 2009Herpetic meningoencephalitis (HME) is a rare but often lethal herpes simplex infection. Patients who survive generally retain neurological deficits. The literature consists mostly of autopsy reports and consistently shows the peripheral and central olfactory pathways to be severely damaged.
Basile Nicolas, Landis +2 more
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Olfactory Dysfunction and Chronic Rhinosinusitis
Immunology and Allergy Clinics of North America, 2020Olfactory dysfunction (OD) is one of the cardinal symptoms of chronic rhinosinusitis (CRS), and its prevalence ranges from 60% to 80% in patients with CRS. It is much more common in CRS with nasal polyposis patients compared to CRS without nasal polyposis. Decreased olfactory function is associated with significant decreases in patient-reported quality
Omar G, Ahmed, Nicholas R, Rowan
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Olfactory Dysfunction After Head Injury
Journal of Head Trauma Rehabilitation, 2008To determine the incidence of olfactory dysfunction after head trauma using clinical and radiologic findings, quantitative assessment, and electro-physiologic methods.A total of 190 patients with head trauma of different severity (n = 32 with mild traumatic brain injury (TBI), n = 94 with signs of moderate TBI, and n = 64 with severe TBI) 6 to 32 ...
Haxel, Boris R +2 more
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Olfactory dysfunction and daily life
European Archives of Oto-Rhino-Laryngology, 2004The objective of the present study was to investigate the hypothesis that subjects with parosmia suffer more in their daily life than patients who experience only quantitative olfactory loss. Two hundred five outpatients of the Smell and Taste Clinic and 25 healthy controls were included.
Johannes, Frasnelli, Thomas, Hummel
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