Results 231 to 240 of about 54,861 (297)

ERα Agonist Protects Aged Female Mice From Sevoflurane Neurotoxicity via PTEN Nuclear Translocation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Repeated sevoflurane exposure induces PTEN nuclear mislocalization, synaptic plasticity impairments, and cognitive deficits in aged female mice, whereas activation of the estrogen receptor α suppresses PTEN nuclear mislocalization, thereby ameliorating synaptic plasticity and cognitive dysfunction.
Xudong Zhang   +7 more
wiley   +1 more source

Progress of Immunotherapies in Parkinson's Disease

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Parkinson's disease (PD) is caused by an immune disorder triggered by α‐synuclein, leading to a persistent neuroinflammatory cycle that drives the disease from non‐motor symptoms to the motor stage. Second, it presents active and passive immunotherapy strategies targeting α‐synuclein and their potential in slowing down the disease progression.
Yong Peng   +10 more
wiley   +1 more source

Standardized Pipeline for Metabolism and Cognition in GO‐DS21 Mouse Model: Investigating Down Syndrome Comorbidities

open access: yesCurrent Protocols, Volume 6, Issue 6, June 2026.
Abstract Down syndrome (DS) is the most prevalent form of intellectual disability (ID) globally, with an incidence rate of approximately 1 in 1000 births, affecting over 5 million individuals worldwide. DS is characterized by a genetic profile that predisposes individuals to a range of medical and cognitive conditions, including ID and obesity, which ...
Mohammed Selloum   +20 more
wiley   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

open access: yesFood Biomacromolecules, Volume 3, Issue 2, Page 237-251, June 2026.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Toxicological Evaluation of the Undesirable Components in Processed Infant Foods Using Artificial Intelligence

open access: yesFuture Postharvest and Food, Volume 3, Issue 2, Page 185-205, June 2026.
The detection of toxins in baby food using artificial intelligence. ABSTRACT Infant foods and baby formulas are becoming increasingly popular across the globe owing to their ease of consumption and nutritional value specific to infants. Impurities may find their way into the food chain at any point from the acquisition of raw materials to final ...
Poornima Singh   +3 more
wiley   +1 more source

Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction. [PDF]

open access: yesInt Forum Allergy Rhinol
Eckert MA   +3 more
europepmc   +1 more source

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