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Olfactory dysfunction in narcolepsy with cataplexy

Sleep Medicine, 2010
Narcolepsy-cataplexy (NC) is caused by the loss of hypocretin neurons. Several lines of evidence suggest a role for hypocretin in olfactory function. Recent data have documented that NC is associated with olfactory dysfunction but smell testing has been performed only in small studies.One hundred thirty NC patients were recruited from two sleep ...
Bayard S.   +5 more
openaire   +2 more sources

Olfactory dysfunctions in neurodegenerative disorders

Journal of Neuroscience Research, 2012
AbstractOlfactory dysfunction is a common symptom in the patients with neurodegenerative disorders, particularly in Parkinson's disease (PD) and Alzheimer's disease (AD). Recently, studies of olfactory dysfunction have focused on its potential as a medication‐independent biomarker for disease progression and as an early indicator for the diagnosis of ...
Yang, Ruan   +4 more
openaire   +2 more sources

Olfactory Dysfunction in Neurodegenerative Diseases

Current Allergy and Asthma Reports, 2018
The sense of smell is today one of the focuses of interest in aging and neurodegenerative disease research. In several neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease, the olfactory dysfunction is one of the initial symptoms appearing years before motor symptoms and cognitive decline, being considered a clinical marker ...
Concepció, Marin   +7 more
openaire   +2 more sources

The Olfactory Dysfunction of COVID-19

Seminars in Neurology, 2023
AbstractUntil the coronavirus disease 2019 (COVID-19) pandemic, much of the scientific community and the general public lacked an appreciation of the impact of decreased smell function on everyday life, including the importance of this sensory system for safety, nutrition, and overall quality of life.
openaire   +2 more sources

Olfactory Dysfunction in Parkinson’s Disease

ORL, 1991
An olfactory function test in 18 patients with Parkinson's disease (PD) and 10 age-matched control subjects was performed. Both detection and recognition thresholds were measured with five kinds of synthesized odorants (T & T olfactometry). Before each test, rhinoscopic inspections were performed to exclude subjects who could have respiratory hyposmia.
T, Murofushi   +3 more
openaire   +2 more sources

Olfactory dysfunction in down's syndrome

Neurobiology of Aging, 1996
Down's Syndrome subjects over 40 years old show neuropathology similar to that of Alzheimer's disease. The olfactory system is particularly vulnerable in Alzheimer's disease, both anatomically and functionally. Several measures of sensory and cognitive functioning were studied in the older Down's Syndrome patient, with the hypothesis of significant ...
C, Murphy, S, Jinich
openaire   +2 more sources

Chronic Rhinosinusitis and Olfactory Dysfunction

2006
Chronic rhinosinusitis encompasses a group of disorders characterized by inflammation of the mucosa of the nose and paranasal sinuses of at least 12 weeks' duration. In addition to nasal obstruction and discharge, chronic sinusitis is a common cause of olfactory dysfunction.
Joseph R, Raviv, Robert C, Kern
openaire   +2 more sources

Olfactory Dysfunction in Allergic Rhinitis

ORL, 2009
<i>Background:</i> Olfactory dysfunction in patients with allergic rhinitis has long been thought to be secondary to coexisting chronic rhinosinusitis and polyposis with obstruction of airflow over the olfactory epithelium. Recent evidence suggests that the allergic inflammatory infiltrate may itself affect olfaction in the absence of ...
Joel, Guss   +3 more
openaire   +2 more sources

Olfactory dysfunction in familial parkinsonism

Neurology, 1997
Impaired olfactory function is commonly observed in idiopathic Parkinson's disease (IPD). However, it is unknown whether it is also found in familial parkinsonism. To address this issue we administered a smell test to 12 affected, three monosymptomatic, and 12 at-risk individuals from six large parkinsonian kindreds.
K, Markopoulou   +6 more
openaire   +2 more sources

A review of olfactory dysfunctions in man

American Journal of Otolaryngology, 1979
Although a large number of individuals experience olfactory disorders following accidents, disease states, medical interventions, aging, and exposure to environmental chemicals and pollutants, few medical practitioners have the expertise or staff to provide appropriate clinical evaluation, treatment, counseling, or referral for such patients.
openaire   +2 more sources

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