Results 231 to 240 of about 92,033 (290)

Deciphering SCN2A: A comprehensive review of rodent models of Scn2a dysfunction

Epilepsia, EarlyView.
Abstract SCN2A encodes for the alpha subunit of the voltage‐gated sodium channel NaV1.2, which is involved in action potential initiation and backpropagation in excitatory neurons. Currently, it is one of the highest monogenetic risk factors for both epilepsy and autism spectrum disorder.
Katelin E. J. Scott, Maria Fernanda Hermosillo Arrieta, Aislinn J. Williams   +2 more
wiley   +1 more source

Nomogram for predicting early olfactory dysfunction in obstructive sleep apnea-hypopnea syndrome: a multicenter-based study. [PDF]

Front Neurol
Pan Q, Yang Q, Huang J, Mi X, Li B.
europepmc   +1 more source

Perception of alcohol strength impaired by low and high volume distraction [PDF]

, 2013
Agobiani, E., Fernandes, M., Stafford, Lorenzo   +2 more
core   +1 more source

C1q neutralization during epileptogenesis attenuates complement‐mediated synaptic elimination and epileptiform activity

Epilepsia, EarlyView.
Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong, Hyun‐Kyoung Lim, Hayeon Kim, Juheon Lee, Siyoon Lee, Minah Suh   +5 more
wiley   +1 more source

Capsaicin and nicotine alleviate MPTP induced olfactory dysfunction by suppressing cGAS/TBK1/STING and MAPK mediated neuroinflammation. [PDF]

NPJ Parkinsons Dis
Wei J, Wang L, Wang D, Chen W, Guo L, Ren M, Guo F, Ruan S, Hu H, Zheng Y, Nan S, Xu Z, Li Y, Yuan H, Mao J, Xu Y, Xie J.   +16 more
europepmc   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

Platelet-Rich Plasma for COVID-19-Related Olfactory Dysfunction: A Systematic Review and Meta-analysis of Randomized Controlled Trials. [PDF]

Cureus
Albazee E, Alajmi SA, Alkandari AM, Aladwani AN, Alenezi YY, Alsaeed MA, Uqlah B, Abu-Zaid A.   +7 more
europepmc   +1 more source

Specific structural changes in Parkinson's disease-related olfactory dysfunction compared to others forms of olfactory dysfunction. [PDF]

Front Neural Circuits
Brosse S, Tremblay C, Mérida I, Frasnelli J.   +3 more
europepmc   +1 more source

Change in healthcare utilization before and after COVID‐19 using data from 1.5 million individuals

Journal of Internal Medicine, EarlyView.
Abstract Background and objective Post‐infectious sequelae can increase burden on healthcare systems. We aimed to assess the long‐term effect of COVID‐19 on healthcare utilization across all levels of care. Methods In this register‐based cohort study, we included all adult (≥18 years) residents in Sweden's two largest counties with a registered COVID ...
Maria Bygdell, Erik Bülow, Simon B. Larsson, Robert Sigström, Huiqi Li, Jari Martikainen, Ailiana Santosa, Lisa Lundberg‐Morris, Susannah Leach, Magnus Gisslén, Carl Bonander, Jörgen Månsson, Kristoffer Strålin, Fredrik Nyberg   +13 more
wiley   +1 more source

Efficacy of Omega-3 supplementation in olfactory dysfunction: a systematic review of randomized controlled trials. [PDF]

BMC Nutr
Alzahrani RS, Alkhatabi TF, Bokhari AF, Ismail WM, Alyamani AS, Alsudais AS, AlRajhi B, Almutairi DM.   +7 more
europepmc   +1 more source