Results 21 to 30 of about 4,174 (181)

Glia control experience-dependent plasticity in an olfactory critical period [PDF]

eLife
Sensory experience during developmental critical periods has lifelong consequences for circuit function and behavior, but the molecular and cellular mechanisms through which experience causes these changes are not well understood. The Drosophila antennal
Hans C Leier, Alexander J Foden, Darren A Jindal, Abigail J Wilkov, Paola Van der Linden Costello, Pamela J Vanderzalm, Jaeda Coutinho-Budd, Masashi Tabuchi, Heather T Broihier   +8 more
doaj   +2 more sources

Considering the Cellular Composition of Olfactory Ensheathing Cell Transplants for Spinal Cord Injury Repair: A Review of the Literature

Frontiers in Cellular Neuroscience, 2021
Olfactory ensheathing cells (OECs) are specialized glia cells of the olfactory system that support the continual regeneration of olfactory neurons throughout adulthood.
Mahjabeen Miah, Patrizia Ferretti, David Choi   +2 more
doaj   +2 more sources

Fibroblast Growth Factor Signaling Instructs Ensheathing Glia Wrapping ofDrosophilaOlfactory Glomeruli [PDF]

Proceedings of the National Academy of Sciences, 2017
AbstractThe formation of complex yet highly organized neural circuits requires interactions between neurons and glia. During the assembly of theDrosophilaolfactory circuit, 50 olfactory receptor neuron (ORN) classes and 50 projection neuron (PN) classes form synaptic connections in 50 glomerular compartments in the antennal lobe, each of which ...
Bing Wu, Jun Li, Ya-Hui Chou, David J. Luginbuhl, Liqun Luo   +4 more
openalex   +5 more sources

Functional Recovery of Paraplegic Rats and Motor Axon Regeneration in Their Spinal Cords by Olfactory Ensheathing Glia [PDF]

Neuron, 2000
Axonal regeneration in the lesioned mammalian central nervous system is abortive, and this causes permanent disabilities in individuals with spinal cord injuries. In adult rats, olfactory ensheathing glia (OEG) transplants successfully led to functional and structural recovery after complete spinal cord transection. From 3 to 7 months post surgery, all
Almudena Ramón‐Cueto, María I. Cordero, Fernando F. Santos‐Benito, Jesús Ávila   +3 more
openalex   +6 more sources

High iron in mouse olfactory ensheathing cells at the glia limitans in the olfactory bulb underlies MRI T2* hypointensity

Imaging Neuroscience
Brain iron is important for normal function, and aberrantly high iron is often associated with neuroinflammation and neurodegeneration. Oligodendrocytes are a major source of iron in brain as are iron-laden activated macrophages and microglia.
Li Liu, Jung-Hwa Tao-Cheng, Hari Rallapalli, Stephen Dodd, Nadia Bouraoud, Alan P. Koretsky   +5 more
openalex   +2 more sources

Expression of plasminogen activator inhibitor‐1 by olfactory ensheathing glia promotes axonal regeneration [PDF]

Glia, 2011
Olfactory ensheathing glia (OEG) cells are known to facilitate repair following axotomy of adult neurons, although the molecular mechanisms involved are not fully understood. We previously identified plasminogen activator inhibitor-1 (PAI-1), proteinase-activated receptor-1 (PAR-1), and thrombomodulin (TM) as candidates to regulate rat OEG-dependent ...
D. Simón, M. J. Martín-Bermejo, Maria Teresa Gallego‐Hernández, Érika Pastrana, Vega García-Escudero, Ana García-Gómez, F. Lim, J. Díaz-Nido, J. Avila, M. Moreno-Flores   +9 more
semanticscholar   +6 more sources

Olfactory Ensheathing Glia: Drivers of Axonal Regeneration in the Central Nervous System? [PDF]

BioMed Research International, 2002
Olfactory ensheathing glia (OEG) accompany olfactory growing axons in their entry to the adult mammalian central nervous system (CNS). Due to this special characteristic, considerable attention has been focused on the possibility of using OEG for CNS regeneration.
María Teresa Moreno-Flores, Javier Díaz‐Nido, Francisco Wandosell, Jesús Ávila   +3 more
openalex   +5 more sources

Glial cells in the mammalian olfactory bulb [PDF]

Frontiers in Cellular Neuroscience
The mammalian olfactory bulb (OB), an essential part of the olfactory system, plays a critical role in odor detection and neural processing. Historically, research has predominantly focused on the neuronal components of the OB, often overlooking the ...
Dan Zhao, Meigeng Hu, Shaolin Liu
doaj   +2 more sources

Olfactory Ensheathing Cells for Spinal Cord Injury

Cell Transplantation, 2018
Olfactory ensheathing cells (OECs) are glia reported to sustain the continuous axon extension and successful topographic targeting of the olfactory receptor neurons responsible for the sense of smell (olfaction).
R. Yao, M. Murtaza, J. Tello Velasquez, M. Todorovic, A. Rayfield, J. Ekberg, M. Barton, J. St John   +7 more
doaj   +2 more sources

Olfactory Ensheathing Glia: Their Application to Spinal Cord Regeneration and Remyelination Strategies [PDF]

Topics in Spinal Cord Injury Rehabilitation, 2000
Grafts of peripheral nerves or peripheral nervous system (PNS) Schwann cells were among the first successful strategies applied to promote regeneration in the central nervous system (CNS). However, glial cells of the PNS and CNS (Schwann cells and astrocytes, respectively) establish borders where they meet, preventing functional reconnection between ...
Naomi Kleitman, Mary Bartlett Bunge
openalex   +3 more sources