Results 21 to 30 of about 1,587 (178)

Axon regeneration can facilitate or suppress hindlimb function after olfactory ensheathing glia transplantation. [PDF]

J Neurosci, 2011
Reports based primarily on anatomical evidence suggest that olfactory ensheathing glia (OEG) transplantation promotes axon regeneration across a complete spinal cord transection in adult rats. Based on functional, electrophysiological, and anatomical assessments, we found that OEG promoted axon regeneration across a complete spinal cord transection and
Takeoka A, Jindrich DL, Muñoz-Quiles C, Muñoz-Quiles C, Zhong H, van den Brand R, Pham DL, Ziegler MD, Ramón-Cueto A, Roy RR, Edgerton VR, Phelps PE.   +11 more
europepmc   +4 more sources

Cell therapy for spinal cord injury with olfactory ensheathing glia cells (OECs) [PDF]

Glia, 2018
AbstractThe prospects of achieving regeneration in the central nervous system (CNS) have changed, as most recent findings indicate that several species, including humans, can produce neurons in adulthood. Studies targeting this property may be considered as potential therapeutic strategies to respond to injury or the effects of demyelinating diseases ...
Rosa Margarita Gómez, Magdy Y. Sánchez, María Portela-Lomba, Kemel A. Ghotme, George E. Barreto, Javier Sierra, María Teresa Moreno-Flores   +6 more
openalex   +6 more sources

A role for gangliosides and β1‐integrin in the motility of olfactory ensheathing glia [PDF]

Journal of Anatomy, 2019
AbstractOlfactory ensheathing glia (OEG) are found in the olfactory mucosa, nerve and bulb, and provide in vivo ensheathment for the unmyelinated olfactory axons within the central and peripheral nervous system domains. OEG cells are able to migrate long distances within the neuropil of the central nervous system.
Alessandra Santos‐Silva, Felipe Márquez Piña‐Rodrigues, Cláudia Mermelstein, Silvana Allodi, Penha C. Barradas, Leny A. Cavalcante   +5 more
openalex   +3 more sources

Olfactory Ensheathing Glia: Their Application to Spinal Cord Regeneration and Remyelination Strategies [PDF]

Topics in Spinal Cord Injury Rehabilitation, 2000
Grafts of peripheral nerves or peripheral nervous system (PNS) Schwann cells were among the first successful strategies applied to promote regeneration in the central nervous system (CNS). However, glial cells of the PNS and CNS (Schwann cells and astrocytes, respectively) establish borders where they meet, preventing functional reconnection between ...
Naomi Kleitman, Mary Bartlett Bunge
openalex   +2 more sources

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis. [PDF]

Glia
Main Points DEOs are similar to satellite glial cells. DECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. ECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs)
Senf K, Nietzsche S, Westermann M, Neuhaus EM.   +3 more
europepmc   +2 more sources

Shared Lineage, Distinct Outcomes: Yap and Taz Loss Differentially Impact Schwann and Olfactory Ensheathing Cell Development Without Disrupting GnRH-1 Migration. [PDF]

Glia
Main Points OECs, SCs, and Mel derive from SCPs. Sox10Cre;YapHet;TazKO mice show impaired SC maturation, reduced Mel formation, fewer SCPs, OECs, and olfactory neurons, but normal GnRH‐1 neuron migration. ABSTRACT Olfactory Ensheathing Cells (OECs) are glial cells originating from the neural crest and are critical for bundling olfactory axons to the ...
Taroc EZM, Amato E, Semon AM, Dolphin N, Beck B, Belin S, Poitelon Y, Forni PE.   +7 more
europepmc   +2 more sources

Further evidence of olfactory ensheathing glia facilitating axonal regeneration after a complete spinal cord transection. [PDF]

Exp Neurol, 2011
Ziegler MD, Hsu D, Takeoka A, Zhong H, Ramón-Cueto A, Phelps PE, Roy RR, Edgerton VR.   +7 more
europepmc   +3 more sources

Glia Preserve Their Own Functions While Compensating for Neighboring Glial Cell Dysfunction. [PDF]

Glia
Main Points When cortex glia lose their interactions with neuronal cell bodies, all neighboring glia infiltrate the region to clear extra neuronal corpses. Even while compensating tor nearby glial dysfunction, glia maintain their own phagocytic Tunctions.
Beachum AN, Salazar G, Nachbar A, Krause K, Klose H, Meyer K, Maserejian A, Ross G, Boyd H, Weigel T, Ambaye L, Miller H, Grote H, Coutinho-Budd J.   +13 more
europepmc   +2 more sources

c-AMP-mediated changes in the intracellular distribution of the myelin-related protein CNPase in olfactory ensheathing glia (OEG) [PDF]

Anais da Academia Brasileira de Ciências, 2000
ALESSANDRA SANTOS-SILVA, LENY A. CAVALCANTE   +1 more
doaj   +2 more sources

Olfactory Nerve Transection Transiently Activates Olfactory Ensheathing Cells in Xenopus laevis Larvae. [PDF]

Eur J Neurosci
The olfactory nerve of larval Xenopus is populated by olfactory ensheathing cells, fibroblasts, and macrophages. Olfactory nerve transection leads to activation of non‐neuronal cells. Activated non‐neuronal cells of the olfactory nerve may support regenerative processes.
Kahl M, Weiss L, Walter J, Hassenklöver T, Manzini I.   +4 more
europepmc   +2 more sources