Results 51 to 60 of about 4,174 (181)
Glia, 2020 Astrocytes are key players in CNS neuroinflammation and neuroregeneration that may help or hinder recovery, depending on the context of the injury. Although pro‐inflammatory factors that promote astrocyte‐mediated neurotoxicity have been shown to be ...
Aybike Saglam, A. Calof, S. Wray
semanticscholar +1 more source
Glial Cell-Axonal Growth Cone Interactions in Neurodevelopment and Regeneration
Frontiers in Neuroscience, 2020 The developing nervous system is a complex yet organized system of neurons, glial support cells, and extracellular matrix that arranges into an elegant, highly structured network.
Michael J. Rigby +8 more
doaj +1 more source
Journal of Integrative Neuroscience, 2023 Background: Glaucoma is the leading cause of irreversible blindness, and the loss of retinal ganglion cells (RGCs) is the most important pathological feature.
Hui Gao +5 more
doaj +1 more source
Chronic Spinal Injury Repair by Olfactory Bulb Ensheathing Glia and Feasibility for Autologous Therapy [PDF]
Journal of Neuropathology & Experimental Neurology, 2009 Olfactory bulb ensheathing glia (OB-OEG) promote repair of spinal cord injury (SCI) in rats after transplantation at acute or subacute (up to 45 days) stages. The most relevant clinical scenario in humans, however, is chronic SCI, in which no more major cellular or molecular changes occur at the injury site; this occurs after the third month in rodents.
Muñoz-Quiles, Cintia +3 more
openaire +4 more sources
Glia, 2020 Olfactory ensheathing cells (OECs) are neural crest‐derived glia that ensheath bundles of olfactory axons from their peripheral origins in the olfactory epithelium to their central targets in the olfactory bulb.
Surangi N Perera +9 more
semanticscholar +1 more source
Olfactory Ensheathing Glia and Spinal Cord Injury: Basic Mechanisms to Transplantation
Future Neurology, 2006 The adult CNS, unlike its counterpart the peripheral nervous system (PNS), has little ability to repair itself after traumatic injury. Therefore, neurotrauma involving the brain or spinal cord has severe and long-lasting functional consequences for injured patients, as well as a massive financial and social impact on the affected families and the ...
Giles W. Plant, Alan R. Harvey
openaire +2 more sources
Olfactory Ensheathing Cells Express α7 Integrin to Mediate Their Migration on Laminin.
PLoS ONE, 2016 The unique glia located in the olfactory system, called olfactory ensheathing cells (OECs), are implicated as an attractive choice for transplantation therapy following spinal cord injury because of their pro-regenerative characteristics.
Norianne T Ingram +2 more
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Olfactory ensheathing cells in facial nerve regeneration
Brazilian Journal of Otorhinolaryngology, 2020 Introduction: Olfactory ensheathing cell is a unique kind of glia cells, which can promote axon growth. Little is known about the differences between olfactory mucosa olfactory ensheathing cells and olfactory bulb olfactory ensheathing cells in the ...
Manyi Li, Qiubei Zhu, Jisheng Liu
doaj
Biology Open, 2017 Perivascular/mural cells originate from either the mesoderm or the cranial neural crest. Regardless of their origin, Notch signalling is necessary for their formation. Furthermore, in both chicken and mouse, constitutive Notch1 activation (via expression
Sophie R. Miller +2 more
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Scientific Reports, 2020 Transplantation of peripheral nervous system glia is being explored for treating neural injuries, in particular central nervous system injuries. These glia, olfactory ensheathing cells (OECs) and Schwann cells (SCs), are thought to aid regeneration by ...
L. Nazareth +8 more
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