Results 71 to 80 of about 1,587 (178)

The Effect of Fetal Olfactory Mucosa on Tissue Sparing and Locomotor Recovery after Spinal Cord Hemisection in Rats [PDF]

open access: yesCell Journal, 2008
Objective: Olfactory ensheathing cells (OECs) has been shown to have a neuroprotectiveeffect after transplanted in brain and spinal cord injury (SCI).
Hamdollah Delaviz   +6 more
doaj  

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 14, Page 3178-3210, July 2025.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

Multiscale Dissection of Spatial Heterogeneity by Integrating Multi‐Slice Spatial and Single‐Cell Transcriptomics

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
Integrating multiple spatial transcriptomics datasets can provide a more comprehensive understanding of tissue structure and cellular heterogeneity. However, batch effects between different slices as well as between spatial transcriptomics and single‐cell reference data bring a great challenge for the integrative analysis.
Yuqi Chen   +4 more
wiley   +1 more source

The cryptonephridial/rectal complex: an evolutionary adaptation for water and ion conservation

open access: yesBiological Reviews, Volume 100, Issue 2, Page 647-671, April 2025.
ABSTRACT Arthropods have integrated digestive and renal systems, which function to acquire and maintain homeostatically the substances they require for survival. The cryptonephridial complex (CNC) is an evolutionary novelty in which the renal organs and gut have been dramatically reorganised. Parts of the renal or Malpighian tubules (MpTs) form a close
Robin Beaven, Barry Denholm
wiley   +1 more source

Schwann Cells and Their Exosomes: Research Progress and Prospect in Spinal Cord Injury

open access: yesNeural Plasticity, Volume 2025, Issue 1, 2025.
Spinal cord injury (SCI) is a severe condition that affects the central nervous system (CNS), for which there is currently no effective treatment. Schwann cells (SCs) transplantation for SCI has been well demonstrated in preclinical studies, showing that it can achieve therapeutic goals by improving autonomic function, reducing neuropathic pain, and ...
Xin Wang   +7 more
wiley   +1 more source

Exosome‐Loaded Bioscaffolds for Spinal Cord Injuries: A Review

open access: yesStem Cells International, Volume 2025, Issue 1, 2025.
Exosomes are naturally occurring cellular products released by various cell types in the body. Their composition is similar to that of human tissues, which reduces the risk of immune rejection. As critical mediators of intercellular communication, exosomes transmit signals and information that regulate the physiological states of surrounding tissues ...
Ruilin Chen   +8 more
wiley   +1 more source

Noninvasive Bioluminescence Imaging of Olfactory Ensheathing Glia and Schwann Cells following Transplantation into the Lesioned Rat Spinal Cord

open access: yesCell Transplantation, 2012
In this study, we assess the feasibility of bioluminescence imaging to monitor the survival of Schwann cells (SCs) and olfactory ensheathing glia cells (OECs) after implantation in the lesioned spinal cord of adult rats.
Kasper C. D. Roet M.Sc.   +2 more
doaj   +1 more source

Olfactory Ensheathing Glia Transplantation Combined with LASERPONCTURE® in Human Spinal Cord Injury: Results Measured by Electromyography Monitoring

open access: yesCell Transplantation, 2010
Preliminary results were measured by electromyography monitoring (electromyoscan) on three subjects suffering from spinal cord injury and who underwent a double therapy.
Albert Bohbot
doaj   +1 more source

Pharmacological, Cell, and Gene Therapy Strategies to Promote Spinal Cord Regeneration

open access: yesCell Transplantation, 2002
In this review, recent studies using pharmacological treatment, cell transplantation, and gene therapy to promote regeneration of the injured spinal cord in animal models will be summarized.
Bas Blits   +2 more
doaj   +1 more source

GENERATION OF FUNCTIONAL NEURONS FROM ADULT HUMAN MUCOSAL OLFACTORY ENSHEATHING GLIA BY DIRECT LINEAGE CONVERSION [PDF]

open access: gold, 2023
María Portela-Lomba   +7 more
openalex   +1 more source

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