Odor coding in the mammalian olfactory epithelium. [PDF]
Cell Tissue Res, 2021 Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs ...
Kurian SM +5 more
europepmc +6 more sources
Persistent post-COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium. [PDF]
Sci Transl Med, 2022 SARS-CoV-2 causes profound changes in the sense of smell, including total smell loss. Although these alterations are often transient, many patients with COVID-19 exhibit olfactory dysfunction that lasts months to years.
Finlay JB +14 more
europepmc +2 more sources
Shedding light on human olfaction: Electrophysiological recordings from sensory neurons in acute slices of olfactory epithelium [PDF]
iScience, 2023 Summary: The COVID-19 pandemic brought attention to our limited understanding of human olfactory physiology. While the cellular composition of the human olfactory epithelium is similar to that of other vertebrates, its functional properties are largely ...
Andres Hernandez-Clavijo +11 more
doaj +3 more sources
Olfactory Regeneration with Nasally Administered Murine Adipose-Derived Stem Cells in Olfactory Epithelium Damaged Mice [PDF]
Cells, 2023 In this study, we aimed to determine whether nasally administered murine adipose-derived stem cells (ADSCs) could support olfactory regeneration in vivo.
Tomoko Ishikura +5 more
doaj +2 more sources
Structural Rearrangement of the Olfactory Epithelium in Male Baikal Yellowfin Sculpins Across the Reproductive Period [PDF]
BiologyThe morphological peculiarities of receptor neurons and support cells in the olfactory epithelium of male yellowfin sculpin (Cottocomephorus grewingkii; Dybowski, 1874) were studied during the pre-spawning, spawning (when males do not feed and have a ...
Igor V. Klimenkov +4 more
doaj +2 more sources
Is TrpM5 a reliable marker for chemosensory cells? Multiple types of microvillous cells in the main olfactory epithelium of mice [PDF]
BMC Neuroscience, 2008 Background In the past, ciliated receptor neurons, basal cells, and supporting cells were considered the principal components of the main olfactory epithelium. Several studies reported the presence of microvillous cells but their function is unknown.
Finger Thomas E, Hansen Anne
doaj +2 more sources
Endogenous pH 6.0 β-Galactosidase Activity Is Linked to Neuronal Differentiation in the Olfactory Epithelium [PDF]
Cells, 2022 The histochemical detection of β-galactosidase enzymatic activity at pH 6.0 (β-gal-pH6) is a widely used biomarker of cellular senescence in aging tissues.
José Antonio de Mera-Rodríguez +6 more
doaj +2 more sources
Science Translational Medicine, 2021 SARS-CoV-2 infects the olfactory epithelium of hamsters and humans and persists in it in individuals with COVID-19 for several months after infection.
G. D. de Melo +20 more
semanticscholar +1 more source
Influence of olfactory epithelium on mitral/tufted cell dendritic outgrowth. [PDF]
PLoS ONE, 2008 Stereotypical connections between olfactory sensory neuron axons and mitral cell dendrites in the olfactory bulb establish the first synaptic relay for olfactory perception.
Ha Tran +4 more
doaj +1 more source
Cell and Tissue Research, 2021 Detection and discrimination of odorants by the olfactory system plays a pivotal role in animal survival. Olfactory-based behaviors must be adapted to an ever-changing environment.
Bertrand Bryche, C. Baly, N. Meunier
semanticscholar +1 more source