Results 1 to 10 of about 371,387 (295)

Neutrophils play a major role in the destruction of the olfactory epithelium during SARS-CoV-2 infection in hamsters. [PDF]

Cell Mol Life Sci, 2022
The loss of smell (anosmia) related to SARS-CoV-2 infection is one of the most common symptoms of COVID-19. Olfaction starts in the olfactory epithelium mainly composed of olfactory sensory neurons surrounded by supporting cells called sustentacular ...
Bourgon C, Albin AS, Ando-Grard O, Da Costa B, Domain R, Korkmaz B, Klonjkowski B, Le Poder S, Meunier N.   +8 more
europepmc   +4 more sources

Persistent post-COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium. [PDF]

Sci Transl Med, 2022
SARS-CoV-2 causes profound changes in the sense of smell, including total smell loss. Although these alterations are often transient, many patients with COVID-19 exhibit olfactory dysfunction that lasts months to years.
Finlay JB, Brann DH, Abi Hachem R, Jang DW, Oliva AD, Ko T, Gupta R, Wellford SA, Moseman EA, Jang SS, Yan CH, Matsunami H, Tsukahara T, Datta SR, Goldstein BJ.   +14 more
europepmc   +2 more sources

Shedding light on human olfaction: Electrophysiological recordings from sensory neurons in acute slices of olfactory epithelium [PDF]

iScience, 2023
Summary: The COVID-19 pandemic brought attention to our limited understanding of human olfactory physiology. While the cellular composition of the human olfactory epithelium is similar to that of other vertebrates, its functional properties are largely ...
Andres Hernandez-Clavijo, Cesar Adolfo Sánchez Triviño, Giorgia Guarneri, Chiara Ricci, Fabian A. Mantilla-Esparza, Kevin Y. Gonzalez-Velandia, Paolo Boscolo-Rizzo, Margherita Tofanelli, Pierluigi Bonini, Michele Dibattista, Giancarlo Tirelli, Anna Menini   +11 more
doaj   +3 more sources

Olfactory Regeneration with Nasally Administered Murine Adipose-Derived Stem Cells in Olfactory Epithelium Damaged Mice [PDF]

Cells, 2023
In this study, we aimed to determine whether nasally administered murine adipose-derived stem cells (ADSCs) could support olfactory regeneration in vivo.
Tomoko Ishikura, Hideaki Shiga, Yuka Nakamura, Takako Kanitani, Yasuhito Ishigaki, Takaki Miwa   +5 more
doaj   +2 more sources

Structural Rearrangement of the Olfactory Epithelium in Male Baikal Yellowfin Sculpins Across the Reproductive Period [PDF]

Biology
The morphological peculiarities of receptor neurons and support cells in the olfactory epithelium of male yellowfin sculpin (Cottocomephorus grewingkii; Dybowski, 1874) were studied during the pre-spawning, spawning (when males do not feed and have a ...
Igor V. Klimenkov, Mikhail V. Pastukhov, Hung-Ming Chang, Ting-Yi Renn, Nikolay P. Sudakov   +4 more
doaj   +2 more sources

Olfactory training changes electrophysiological responses at the level of the olfactory epithelium

Rhinology, 2018
BACKGROUND Olfactory training (OT) has been shown to increase olfactory performance in healthy subjects and patients with post-traumatic or post-infectious olfactory loss.
Thomas Hummel, G. Stupka, Antje Haehner, Sophia C. Poletti   +3 more
openalex   +3 more sources

Ascl1 (Mash1) Knockout Perturbs Differentiation of Nonneuronal Cells in Olfactory Epithelium

PLoS ONE, 2012
The embryonic olfactory epithelium (OE) generates only a very few olfactory sensory neurons when the basic helix-loop-helix transcription factor, ASCL1 (previously known as MASH1) is eliminated by gene mutation. We have closely examined the structure and
Richard C. Krolewski, Adam Packard, Woochan Jang, Hendrik Wildner, James E. Schwob   +4 more
openalex   +3 more sources

Identity, lineage and fates of a temporally distinct progenitor population in the embryonic olfactory epithelium. [PDF]

Dev Biol, 2023
Paronett EM, Bryan CA, Maynard TM, LaMantia AS.   +3 more
europepmc   +2 more sources

Paired and solitary ionocytes in the zebrafish olfactory epithelium [PDF]

Chem Senses
Peloggia J, Cheung KY, Petkova MD, Schalek R, Boulanger-Weill J, Wu Y, Wang S, van Hateren NJ, Januszewski M, Jain V, Lichtman JW, Engert F, Piotrowski T, Whitfield TT, Jesuthasan S.   +14 more
europepmc   +3 more sources

Biopsy of the olfactory epithelium from the superior nasal septum: is it possible to obtain neurons without damaging olfaction?

Brazilian Journal of Otorhinolaryngology, 2022
Introduction: Olfactory epithelium biopsy has been useful for studying diverse otorhinolaryngological and neurological diseases, including the potential to better understand the pathophysiology behind COVID-19 olfactory manifestations.
Ellen Cristine Duarte Garcia, Lucas de Almeida Luz, Lucas Kanieski Anzolin, José Lucas Barbosa da Silva, Richard L. Doty, Fábio de Rezende Pinna, Richard Louis Voegels, Marco Aurélio Fornazieri   +7 more
doaj   +1 more source