Results 91 to 100 of about 396,689 (323)

Expression of CD36 by Olfactory Receptor Cells and Its Abundance on the Epithelial Surface in Mice. [PDF]

PLoS ONE, 2015
CD36 is a transmembrane protein that is involved in the recognition of certain amphiphilic molecules such as polar lipids in various tissues and body fluids.
Shinhye Lee, Ai Eguchi, Satoshi Tsuzuki, Shigenobu Matsumura, Kazuo Inoue, Toshihiko Iwanaga, Daisaku Masuda, Shizuya Yamashita, Tohru Fushiki   +8 more
doaj   +1 more source

mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium

PLoS Genetics, 2016
Neurogenesis is a key developmental event through which neurons are generated from neural stem/progenitor cells. Chromatin remodeling BAF (mSWI/SNF) complexes have been reported to play essential roles in the neurogenesis of the central nervous system ...
Christina Bachmann, H. Nguyen, Joachim Rosenbusch, Linh Pham, Tamara I Rabe, Megha Patwa, G. Sokpor, R. Seong, R. Ashery-Padan, A. Mansouri, Anastassia Stoykova, J. Staiger, Tran Tuoc   +12 more
semanticscholar   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Intensity Coding in Two-Dimensional Excitable Neural Networks

, 2004
In the light of recent experimental findings that gap junctions are essential for low level intensity detection in the sensory periphery, the Greenberg-Hastings cellular automaton is employed to model the response of a two-dimensional sensory network to ...
Bair, Bardou, Bokil, Chialvo, Cleland, Copelli, Deans, Firestein, Greenberg, Hidaka, Kaplan, Kosaka, Lewis, Mauro Copelli, Osame Kinouchi, Purves, Rospars, Simões-de-Souza, Stevens, Tomé, Traub, Wiener, Zhang, Zorzenon dos Santos   +23 more
core   +2 more sources

Neurons and circuits for odor processing in the piriform cortex [PDF]

, 2013
Increased understanding of the early stages of olfaction has lead to a renewed interest in the higher brain regions responsible for forming unified ‘odor images’ from the chemical components detected by the nose.
Bekkers, John MacDonald, Suzuki, Norimitsu   +1 more
core   +1 more source

Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]

, 2020
Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul, De Herdt, Veerle, Garrez, Ieme, Hemelsoet, Dimitri, Laureys, Guy, Raedt, Robrecht, Vonck, Kristl   +6 more
core   +2 more sources

Combining skin and olfactory α-synuclein seed amplification assays (SAA)—towards biomarker-driven phenotyping in synucleinopathies

npj Parkinson's Disease, 2023
Seed amplification assays (SAA) are becoming commonly used in synucleinopathies to detect α-synuclein aggregates. Studies in Parkinson’s disease (PD) and isolated REM-sleep behavior disorder (iRBD) have shown a considerably lower sensitivity in the ...
A. Kuzkina, J. Rößle, A. Seger, C. Panzer, A. Kohl, V. Maltese, T. Musacchio, S. Blaschke, G. Tamgüney, S. Kaulitz, K. Rak, A. Scherzad, P. H. Zimmermann, J. Klussmann, S. Hackenberg, J. Volkmann, C. Sommer, M. Sommerauer, K. Doppler   +18 more
semanticscholar   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium

Scientific Reports, 2016
The sensory neurons in the olfactory epithelium (OSNs) are equipped with a large repertoire of olfactory receptors and the associated signal transduction machinery.
A. M. Xavier, R. G. Ludwig, Maíra H. Nagai, Tiago Jonas de Almeida, Hebe Mizuno Watanabe, Marcio Yukio Hirata, T. Rosenstock, F. Papes, B. Malnic, I. Glezer   +9 more
semanticscholar   +1 more source

Biomarker‐Agnostic Detection of Ovarian Cancer from Blood Plasma Using a Machine Learning‐Driven Electronic Nose

Advanced Intelligent Systems, EarlyView.
This study introduces a biomarker‐agnostic diagnostic strategy for ovarian cancer, utilizing a machine learning‐enhanced electronic nose to analyze volatile organic compound signatures from blood plasma. By overcoming the dependence on specific biomarkers, this approach enables accurate detection, staging, and cancer type differentiation, offering a ...
Ivan Shtepliuk, Lingyin Meng, Christer Borgfeldt, Jens Eriksson, Donatella Puglisi   +4 more
wiley   +1 more source