Results 181 to 190 of about 388,373 (393)

Nose‐to‐Brain Delivery of Acyl‐Ghrelin Peptide Gold Nanoconjugates for Treatment of Neurodegenerative Diseases

open access: yesSmall, EarlyView.
Intranasal delivery of acyl‐ghrelin using gold nanorods (AuNRs) is investigated as a strategy for treating neurodegenerative diseases. Acyl‐ghrelin is conjugated to AuNRs under optimized conditions that preserve its bioactivity and prevent nanoparticle cross‐linking.
Shunping Han   +6 more
wiley   +1 more source

Proliferative and neoplastic aural pinna masses in a collection of African giant pouched rats (Cricetomys ansorgei)

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract This case series describes aural lesions occurring in five African giant pouched rats (Cricetomys ansorgei) residing at a single zoological institution in southern California. Age of onset ranged from 3 to 7 years. Lesions occurred as single or multiple masses on one or both ears. A single case also developed a nasal mass.
Amanda Burke   +4 more
wiley   +1 more source

Adaptation of olfactory receptor abundances for efficient coding

open access: yes, 2019
Olfactory receptor usage is highly heterogeneous, with some receptor types being orders of magnitude more abundant than others. We propose an explanation for this striking fact: the receptor distribution is tuned to maximally represent information about ...
Balasubramanian, Vijay   +3 more
core   +1 more source

The characteristics of sinonasal inverted papilloma and recurrence factors: An analysis of 207 cases

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
Abstract Objectives Sinonasal inverted papilloma (IP) is a rare and benign tumor that affects the nose and sinuses. This tumor has a recurring nature and can be associated with malignancy or transform into a malignant lesion. Various factors have been proposed as potential recurrent and malignancy risk factors in sinonasal IP.
SeyedHadi SamimiArdestani   +8 more
wiley   +1 more source

Plastamination: A Rising Concern for Parkinson's Disease

open access: yes
Movement Disorders, EarlyView.
Roberto Erro   +2 more
wiley   +1 more source

Current Insights Into Individualized Diagnosis and Treatment of Allergic Rhinitis Based on Phenotype and Endotype

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu   +7 more
wiley   +1 more source

The $Ca^{2+}$-activated $Cl^-$ current ensures robust and reliable signal amplification in vertebrate olfactory receptor neurons

open access: yes, 2018
Activation of most primary sensory neurons results in transduction currents that are carried by cations. One notable exception is the vertebrate olfactory receptor neuron (ORN), where the transduction current is carried largely by the anion $Cl ...
Reingruber, Jürgen, Reisert, Johannes
core  

Secreted factors from olfactory mucosa cells expanded as free-floating spheres increase neurogenesis in olfactory bulb neurosphere cultures. [PDF]

open access: yes, 2011
BACKGROUND: The olfactory epithelium is a neurogenic tissue comprising a population of olfactory receptor neurons that are renewed throughout adulthood by a population of stem and progenitor cells.
Barraud, Perrine   +3 more
core  

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