Results 21 to 30 of about 50,842 (231)

Biopsies of Human Olfactory Epithelium [PDF]

Chemical Senses, 2002
It has been shown that olfactory epithelium can be safely biopsied from the living, intact human being. Observations of the ultrastructure of this epithelium shows changes that can then be correlated with the etiology and degree of olfactory loss, allowing a greater understanding of both normal transduction and of the pathology of dysfunction. Examples
Bruce W, Jafek, B, Murrow, R, Michaels, D, Restrepo, M, Linschoten   +4 more
openaire   +2 more sources

Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. [PDF]

PLoS ONE, 2015
TMEM16A/ANO1 is a calcium-activated chloride channel expressed in several types of epithelia and involved in various physiological processes, including proliferation and development.
Devendra Kumar Maurya, Tiago Henriques, Monica Marini, Nicoletta Pedemonte, Luis J V Galietta, Jason R Rock, Brian D Harfe, Anna Menini   +7 more
doaj   +1 more source

Grafting the Olfactory Epithelium to the Olfactory Bulb [PDF]

American Journal of Rhinology & Allergy, 2009
Background Impaired olfactory function leads to a decrease in the quality of life for many patients. Surgical treatment options are limited, especially for those suffering from hyposmia or anosmia after posttraumatic injury to the olfactory nerves. Stem cells located in the olfactory epithelium (OE) have the capacity to grow new neurons, making the OE ...
Sayaka, Yagi, Richard M, Costanzo
openaire   +2 more sources

Effect of acute copper sulfate exposure on olfactory responses to amino acids and pheromones in goldfish (Carassius auratus) [PDF]

, 2009
Exposure of olfactory epithelium to environmentally relevant concentrations of copper disrupts olfaction in fish. To examine the dynamics of recovery at both functional and morphological levels after acute copper exposure, unilateral exposure of ...
Baldwin D. H., Beyers D. W., Boulay N., Carreau N. D., Chen T. G., De Boeck G., De Boeck G., Dittman A., Evans R. E., Gao X. L., Graziadei G. A., Hansen A., Hansen A., Hansen J. A., Hansen J. A., Hara T. J., Hubbard P. C., Hubbard P. C., Jennings R. A., Julliard A. K., Julliard A. K., Julliard A. K., Keller J. N., Kolmakov N. N., Konzelmann S., Kotrschal K., Mangos S., Masukawa L. M., McIntyre J. K., Moran D. T., Nair A. V., Nikonov A. A., Niyogi S., Pyle G. G., Rolen S. H., Saglio P., Sandahl J. F., Sandahl J. F., Sandahl J. F., Sato Y., Saucier D., Sloman K. A., Sorensen P., Sorensen P. W., Sorensen P. W., Stacey N., Starcevic S. L., Susankova K., Tilton F., Wang R. T., Winberg S., Zippel H. P., Zippel H. P.   +52 more
core   +2 more sources

Olfactory and solitary chemosensory cells: two different chemosensory systems in the nasal cavity of the American alligator, Alligator mississippiensis

BMC Neuroscience, 2007
Background The nasal cavity of all vertebrates houses multiple chemosensors, either innervated by the Ist (olfactory) or the Vth (trigeminal) cranial nerve. Various types of receptor cells are present, either segregated in different compartments (e.g. in
Hansen Anne
doaj   +1 more source

Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons. [PDF]

PLoS ONE, 2013
The Ca(2+)-activated Cl(-) channel is considered a key constituent of odor transduction. Odorant binding to a specific receptor in the cilia of olfactory sensory neurons (OSNs) triggers a cAMP cascade that mediates the opening of a cationic cyclic ...
Carolina Gonzalez-Silva, Jorge Vera, María Rosa Bono, Christian González-Billault, Brooke Baxter, Anne Hansen, Robert Lopez, Emily A Gibson, Diego Restrepo, Juan Bacigalupo   +9 more
doaj   +1 more source

Olfactory Rod Cells: A Rare Cell Type in the Larval Zebrafish Olfactory Epithelium With a Large Actin-Rich Apical Projection

Frontiers in Physiology, 2021
We report the presence of a rare cell type, the olfactory rod cell, in the developing zebrafish olfactory epithelium. These cells each bear a single actin-rich rod-like apical projection extending 5–10 μm from the epithelial surface.
King Yee Cheung, Suresh J. Jesuthasan, Suresh J. Jesuthasan, Sarah Baxendale, Nicholas J. van Hateren, Mar Marzo, Christopher J. Hill, Tanya T. Whitfield   +7 more
doaj   +1 more source

Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]

, 1993
The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer, Bergmann, Betz, Bixby, Breipohl, Brunjes, Elferink, Farbman, Farbman, Fletcher, Geppert, Gesteland, Graziadei, Halász, Halász, Hinds, Hsu, Huttner, Jahn, Jahn, Knaus, Kosaka, Lahr, Lahr, Leube, Mandell, Marchand, Margolis, Marquèze-Pouey, Matteoli, McLean, Navone, Ovtscharoff, Pedersen, Rehn, Schwob, Schwob, Shipley, Smotherman, Specht, Specht, Südhof, Thomas, Thomas, Tixier-Vidal, Trimble, Van Lookeren Campagne, Verhaagen, Wendland, Wiedenmann, Zhong   +50 more
core   +1 more source

Canonical Wnt Signaling Drives Tumor-Like Lesions from Sox2-Positive Precursors of the Murine Olfactory Epithelium. [PDF]

PLoS ONE, 2016
Canonical Wnt signaling is known to promote proliferation of olfactory stem cells. In order to investigate the effects of a constitutive activation of Wnt signaling in Sox2-positive precursor cells of the olfactory epithelium, we used transgenic mice ...
Nils W Engel, Julia E Neumann, Julia Ahlfeld, Annika K Wefers, Daniel J Merk, Jasmin Ohli, Ulrich Schüller   +6 more
doaj   +1 more source

The Microvillar and Solitary Chemosensory Cells as the Novel Targets of Infection of SARS-CoV-2 in Syrian Golden Hamsters

Viruses, 2021
Patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019, suffer from respiratory and non-respiratory symptoms. Among these symptoms, the loss of smell has attracted considerable
Jin-Seok Seo, Sun-Woo Yoon, Seung-Hyeon Hwang, Sung-Min Nam, Sang-Soep Nahm, Jei-Hyun Jeong, Jiho Lee, Ha-Na Youn, Jun-Beom Kim, Woosuk Kim   +9 more
doaj   +1 more source