Results 321 to 330 of about 388,373 (393)
Role of NRP1/HDAC4/CREB/RIPK1 Axis in SARS‐CoV2 S1 Spike Subunit‐Induced Neuronal Toxicity
FASEB BioAdvances, Volume 7, Issue 8, August 2025.Extracellular SARS‐CoV2 Spike‐S1 protein via NRP1 internalizes in the cytosol of SH‐SY5Y cells. Once inside, it upregulates the epigenetic eraser HDAC4, which binds transcriptional factor CREB, causes RIPK1 up‐regulation, and therefore necroptotic cell death.
Luca Sanguigno +8 more
wiley +1 more source
Acta Physiologica, Volume 241, Issue 8, August 2025.ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth +2 more
wiley +1 more source
V‐ATPase expression in the mouse olfactory epithelium
, 2007 Teodor G. Păunescu +2 more
openalex +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.This schematic depicts the proposed mechanism by which TMAO alleviates PND by modulating neuroinflammation in the hippocampus. Anesthesia and surgery disrupt the balance between pro‐inflammatory (e.g., IL‐1β, TNF‐α) and anti‐inflammatory cytokines (e.g., TGF‐β), promoting M1 microglial polarization and cognitive impairment.
Mengxin Que +7 more
wiley +1 more source
Cell Proliferation, Volume 58, Issue 8, August 2025.Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin +4 more
wiley +1 more source
Cell Proliferation, Volume 58, Issue 8, August 2025.The cover image is based on the article Deficiency of Aging‐Related Gene Chitinase‐Like 4 Impairs Olfactory Epithelium Homeostasis by Tingting Wu et al., https://doi.org/10.1111/cpr.70055. The cover image is based on the article Deficiency of Aging‐Related Gene Chitinase‐Like 4 Impairs Olfactory Epithelium Homeostasis by Tingting Wu et al., https://doi.
Tingting Wu +7 more
wiley +1 more source
European Journal of Neuroscience, Volume 62, Issue 3, August 2025.The olfactory nerve of larval Xenopus is populated by olfactory ensheathing cells, fibroblasts, and macrophages. Olfactory nerve transection leads to activation of non‐neuronal cells. Activated non‐neuronal cells of the olfactory nerve may support regenerative processes.
Melina Kahl +4 more
wiley +1 more source
European Journal of Neurology, Volume 32, Issue 8, August 2025.We review the non‐motor symptoms of MG and their potential pathogenesis, hoping to contribute to personalized diagnosis and treatment. ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder affecting the neuromuscular junction (NMJ), driven by T cells, mediated by B cells, and dependent on autoantibodies.
Benqiao Wang +3 more
wiley +1 more source