Results 341 to 350 of about 388,373 (393)

Trpm5 expression in the olfactory epithelium

Molecular and Cellular Neuroscience, 2017
The Ca2+-activated monovalent cation channel Trpm5 is a key element in chemotransduction of taste receptor cells of the tongue, but the extent to which Trpm5 channels are expressed in olfactory sensory neurons (OSNs) of the main olfactory epithelium (MOE) of adult mice as part of a specific pheromonal detection system is debated.
Martina Pyrski, Eugenia Eckstein, Andreas Schmid, Bernd Bufe, Jan Weiss, Vladimir Chubanov, Ulrich Boehm, Frank Zufall   +7 more
openaire   +3 more sources

Endocannabinoid Modulation in the Olfactory Epithelium

2010
Appetite, food intake, and energy balance are closely linked to the endocannabinoid system in the central nervous system. Now, endocannabinoid modulation has been discovered in the peripheral olfactory system of larval Xenopus laevis. The endocannabinoid 2-AG has been shown to influence odorant-detection thresholds according to the hunger state of the ...
Breunig E, Czesnik D, Piscitelli F, Di Marzo V, Manzini I, Schild D   +5 more
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Apoptosis in the Aging Olfactory Epithelium

The Laryngoscope, 2002
AbstractObjectives Olfactory receptor neurons undergo apoptosis at a baseline rate, probably secondary to environmental damage even in the absence of gross disease. The study demonstrates age‐related changes in expression of genes known to regulate apoptosis in the rat olfactory mucosa.
Robert C. Kern, Michael J. Shinners, David B. Conley, Alan M. Robinson   +3 more
openaire   +3 more sources

Cell death in the olfactory epithelium

Anatomy and Embryology, 1995
In the nervous system of vertebrates the olfactory epithelium presents unique cytological characteristics. In the olfactory mucosa, olfactory neurons die and are replaced from undifferentiated neuroblasts over the entire life span of the animal. It remains unclear whether these neurons die as a result of a direct insult from the environment or in ...
MAGRASSI, LORENZO, P. P. Graziadei
openaire   +3 more sources

Regeneration of rabbit olfactory epithelium

American Journal of Anatomy, 1971
AbstractEpithelial regeneration was determined with light and electron microscopy after preferential chemical destruction of olfactory epithelium in rabbits. Regeneration of either olfactory epithelium, ciliated columnar epithelium or a mixture of the two occurred.
Bruce D. Mulvaney, Herbert E Heist
openaire   +3 more sources

‘On’- and ‘Off’- Responses of the Olfactory Epithelium

Nature, 1959
SLOW-action potentials have been found in various sensory receptors in response to adequate stimuli. They were first found in the olfactory epithelium of a dog by Hosoya and Yoshida1. Recently, Ottoson2 studied them extensively in the olfactory epithelium of a frog.
Sadayuki F. Takagi, T. Shibuya
openaire   +3 more sources

Neurotrophin expression in the adult olfactory epithelium

Brain Research, 2008
Published reports of neurotrophin expression in the olfactory system are incomplete because of missing data and conflicting results. Previous studies used a variety of fixation procedures and antibodies on different species and different ages. The aim of the present study was to examine expression of neurotrophins and their receptors using optimized ...
Francois Feron, John Bianco, John Bianco, Alan Mackay-Sim, Ian A. Ferguson   +4 more
openaire   +5 more sources

Endothelin as a neuroprotective factor in the olfactory epithelium

Neuroscience, 2011
In mammals, the olfactory sensory neurons are the only ones directly in contact with an aggressive environment. Thus, the olfactory mucosa is one of the few neuronal zones which are continuously renewed during adulthood. We have previously shown that endothelin is locally matured in the olfactory mucosa and that olfactory sensory neurons preferentially
I. Laziz, Patrice Congar, M. Sautel, M. Sautel, Marie-Christine Lacroix, Nicolas Meunier, Nicolas Meunier, Aniya Larbi, Roland Salesse, Denise Grebert   +9 more
openaire   +5 more sources

Nose-to-Brain Delivery: Investigation of the Transport of Nanoparticles with Different Surface Characteristics and Sizes in Excised Porcine Olfactory Epithelium.

Molecular Pharmaceutics, 2015
The ability to deliver therapeutically relevant amounts of drugs directly from the nasal cavity to the central nervous system to treat neurological diseases is dependent on the availability of efficient drug delivery systems.
A. Mistry, S. Stolnik, L. Illum
semanticscholar   +1 more source

Olfaction and neurogenesis in the olfactory epithelium [PDF]

Neurophysiology, 1991
Anosmia was experimentally produced in strain C57BL/6 laboratory mice by treatment with 1% zinc sulfate solution. Structural and functional changes taking place in the olfactory epithelium were investigated during this process and during reinstatement of olfaction.
V. T. Troitskaya, O. S. Gladysheva
openaire   +1 more source