Results 71 to 80 of about 371,387 (295)
npj Parkinson's Disease, 2023 Seed amplification assays (SAA) are becoming commonly used in synucleinopathies to detect α-synuclein aggregates. Studies in Parkinson’s disease (PD) and isolated REM-sleep behavior disorder (iRBD) have shown a considerably lower sensitivity in the ...
A. Kuzkina +18 more
semanticscholar +1 more source
Artificial Intelligence Revolution in Transcriptomics: From Single Cells to Spatial Atlases
Advanced Science, EarlyView.Single‐cell RNA sequencing and spatial transcriptomics have unveiled cellular heterogeneity and tissue organization with unprecedented resolution. Artificial intelligence (AI) now plays a pivotal role in interpreting these complex data. This review systematically surveys AI applications across the entire analytic workflow and offers practical guidance ...
Shixin Li +7 more
wiley +1 more source
Adiponectin enhances the responsiveness of the olfactory system. [PDF]
PLoS ONE, 2013 The peptide hormone adiponectin is secreted by adipose tissue and the circulating concentration is reversely correlated with body fat mass; it is considered as starvation signal.
Diana Loch +3 more
doaj +1 more source
CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium
Scientific Reports, 2016 The sensory neurons in the olfactory epithelium (OSNs) are equipped with a large repertoire of olfactory receptors and the associated signal transduction machinery.
A. M. Xavier +9 more
semanticscholar +1 more source
Advanced Intelligent Systems, EarlyView.gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley +1 more source
Heliyon, 2018 Thyroid hormone (TH) plays an important role in regulating multiple cellular and metabolic processes, including cell proliferation, cell death, and energy metabolism, in various organs and tissues of vertebrates.
Hideaki Kudo +3 more
doaj +1 more source
Data from Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma
, 2023 <div><p>Olfactory neuroblastoma is a rare tumor arising from the olfactory cleft region of the nasal cavity. Because of the low incidence of this tumor, as well as an absence of established cell lines and murine models, understanding the mechanisms driving olfactory neuroblastoma pathobiology has been challenging.
Bradley J. Goldstein +4 more
openaire +1 more source
Advanced Intelligent Systems, EarlyView.This study introduces a biomarker‐agnostic diagnostic strategy for ovarian cancer, utilizing a machine learning‐enhanced electronic nose to analyze volatile organic compound signatures from blood plasma. By overcoming the dependence on specific biomarkers, this approach enables accurate detection, staging, and cancer type differentiation, offering a ...
Ivan Shtepliuk +4 more
wiley +1 more source
Disparity of turbinal bones in placental mammals
The Anatomical Record, EarlyView.Abstract Turbinals are key bony elements of the mammalian nasal cavity, involved in heat and moisture conservation as well as olfaction. While turbinals are well known in some groups, their diversity is poorly understood at the scale of placental mammals, which span 21 orders.
Quentin Martinez +11 more
wiley +1 more source
PLoS ONE, 2012 Neurogenesis continues in the adult brain and in the adult olfactory epithelium. The cytokine, leukaemia inhibitory factor and nitric oxide are both known to stimulate neuronal progenitor cell proliferation in the olfactory epithelium after injury.
Estefania Lopez-Arenas +3 more
doaj +1 more source