Results 21 to 30 of about 149,007 (299)
YAC transgene-mediated olfactory receptor gene choice [PDF]
Developmental Dynamics, 2000 In the mouse, individual olfactory neurons express one of a thousand distinct olfactory receptor genes. Furthermore, only one allele of the expressed gene is transcribed. This phenomenon, random allelic inactivation, along with the observation that the olfactory receptor genes reside in large chromosomal arrays, suggests a role for long-range gene ...
F A, Ebrahimi +3 more
openaire +2 more sources
Advances in the Study of Olfaction in Eusocial Ants
Insects, 2021 Over the past decade, spurred in part by the sequencing of the first ant genomes, there have been major advances in the field of olfactory myrmecology.
Stephen T. Ferguson +2 more
doaj +1 more source
Competence, specification and commitment to an olfactory placode fate [PDF]
, 2008 The nasal placode shares a common origin with other sensory placodes within a pre-placodal domain at the cranial neural plate border. However, little is known about early events in nasal placode development as it segregates from prospective lens, neural ...
Bhattacharyya, Sujata +1 more
core +2 more sources
Promoter architecture of mouse olfactory receptor genes [PDF]
Genome Research, 2011 Odorous chemicals are detected by the mouse main olfactory epithelium (MOE) by about 1100 types of olfactory receptors (OR) expressed by olfactory sensory neurons (OSNs). Each mature OSN is thought to express only one allele of a single OR gene. Major impediments to understand the transcriptional control of OR gene expression are the lack of a proper ...
Plessy, Charles +18 more
openaire +8 more sources
An Olfactory Receptor Pseudogene whose Function emerged in Humans [PDF]
, 2007 Human olfactory receptor, hOR17-210, is identified as a pseudogene in the human genome. Experimental data has shown however, that the gene product of cloned hOR17-210 cDNA was able to bind an odorant-binding protein and is narrowly tuned for excitation ...
Catherine Ronin +6 more
core +2 more sources
Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1-/- mice. [PDF]
, 2010 An ongoing controversy exists on beneficial versus harmful effects of high beta-carotene (BC) intake, especially for the lung. To elucidate potential mechanisms, we studied effects of BC on lung gene expression.
Amengual, J. +9 more
core +2 more sources
Widespread ectopic expression of olfactory receptor genes [PDF]
BMC Genomics, 2006 Abstract Background Olfactory receptors (ORs) are the largest gene family in the human genome. Although they are expected to be expressed specifically in olfactory tissues, some ectopic expression has been reported, with special emphasis on sperm and testis.
Yanai Itai +5 more
openaire +3 more sources
Otx2 expression and implications for olfactory imprinting in the anemonefish, Amphiprion percula
Biology Open, 2013 Summary The otx2 gene encodes a transcription factor (OTX2) essential in the formation of the brain and sensory systems. Specifically, OTX2-positive cells are associated with axons in the olfactory system of mice and otx2 is upregulated in odour-exposed ...
Heather D. Veilleux +7 more
doaj +1 more source
High-resolution mapping of cancer cell networks using co-functional interactions. [PDF]
, 2018 Powerful new technologies for perturbing genetic elements have recently expanded the study of genetic interactions in model systems ranging from yeast to human cell lines.
Boyle, Evan A +2 more
core +1 more source
Singular Expression of Olfactory Receptor Genes [PDF]
Cell, 2013 Understanding the mechanisms of monogenic and monoallelic transcription of the large repertoire of olfactory receptor genes represents a challenging task. A picture is now emerging in which odorant receptor choice and stabilization involve an escape from silencing followed by the activation of an unconventional feedback loop.
openaire +3 more sources