Results 41 to 50 of about 149,007 (299)

Neurodegeneration in the olfactory bulb and olfactory deficits in the Ccdc66 -/- mouse model for retinal degeneration

open access: yesIBRO Reports, 2018
The Ccdc66-deficient (Ccdc66 -/-) mouse model exhibits slow progressive retinal degeneration. It is unclear whether CCDC66 protein also plays a role in the wildtype (WT; Ccdc66 +/+) mouse brain and whether the lack of Ccdc66 gene expression in the Ccdc66
Sabrina Schreiber   +5 more
doaj   +1 more source

Influence of blood meal on the responsiveness of olfactory receptor neurons in antennal sensilla trichodea of the yellow fever mosquito, Aedes aegypti [PDF]

open access: yes, 2010
In female Aedes aegypti L. mosquitoes, a blood meal induces physiological and behavioral changes. Previous studies have shown that olfactory receptor neurons (ORNs) housed in grooved peg sensilla on the antennae of Ae.
Hansson, Bill   +3 more
core   +1 more source

Unfolding the Mystery of Olfactory Receptor Gene Expression [PDF]

open access: yesDevelopmental Cell, 2013
Reporting recently in Cell, Dalton et al. (2013) identify a central role for the unfolded protein response in the regulation of olfactory receptor expression, unveiling molecular players in an elaborate feedback loop that controls the stabilization and establishment of single olfactory receptor gene choice.
Li, Yun Rose, Matsunami, Hiroaki
openaire   +2 more sources

Anti-high mobility group box 1 antibody suppresses local inflammatory reaction and facilitates olfactory nerve recovery following injury

open access: yesJournal of Neuroinflammation, 2018
Background Refractory olfactory dysfunction is a common finding in head trauma due to olfactory nerve injury. Anti-inflammatory treatment using steroids is known to contribute to functional recovery of the central and peripheral nervous systems in injury
Masayoshi Kobayashi   +4 more
doaj   +1 more source

Persistent and transient olfactory deficits in COVID-19 are associated to inflammation and zinc homeostasis

open access: yesFrontiers in Immunology, 2023
IntroductionThe Coronavirus Disease 2019 (COVID-19) is mainly a respiratory syndrome that can affect multiple organ systems, causing a variety of symptoms.
Lorenzo Lupi   +16 more
doaj   +1 more source

Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb [PDF]

open access: yes, 2007
The formation of precise stereotypic connections in sensory systems is critical for the ability to detect and process signals from the environment. In the olfactory system, olfactory sensory neurons (OSNs) project axons to spatially defined glomeruli ...
Andrews, W   +4 more
core   +1 more source

Olfactory receptor gene abundance in invasive breast carcinoma [PDF]

open access: yesScientific Reports, 2019
AbstractExpression of olfactory receptors (ORs) has been reported in many human tissues outside the nasal epithelium. ORs have been validated as biomarkers in prostate cancer. In breast cancer, however, the expression and role of OR genes remain understudied.
Masjedi, Shirin   +2 more
openaire   +2 more sources

Mapping transgene insertion sites reveals the α-Cre transgene expression in both developing retina and olfactory neurons

open access: yesCommunications Biology, 2022
The Pax6-α-Cre mouse line used in retinal studies actually contains four transgene insertion within gene clusters of olfactory and vomeronasal receptors, leading to expression in not just retinal, but also olfactory and vomeronasal sensory neurons.
Yimeng Fan   +7 more
doaj   +1 more source

Activity-Dependent Genes in Mouse Olfactory Sensory Neurons [PDF]

open access: yesChemical Senses, 2014
Activity-dependent survival of olfactory sensory neurons (OSNs) may allow animals to tune their olfactory systems to match their odor environment. Activity-dependent genes should play important roles in this process, motivating experiments to identify them.
Adrian M, Fischl   +3 more
openaire   +2 more sources

Detection and localization of the thyroid hormone receptor beta mRNA in the immature olfactory receptor neurons of chum salmon

open access: yesHeliyon, 2018
Thyroid hormone (TH) plays an important role in regulating multiple cellular and metabolic processes, including cell proliferation, cell death, and energy metabolism, in various organs and tissues of vertebrates.
Hideaki Kudo   +3 more
doaj   +1 more source

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