Results 141 to 150 of about 393,252 (329)
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT The U.S. Food and Drug Administration (FDA) publishes product‐specific guidances (PSGs), with bioequivalence (BE) recommendations for prospective generics. Developing BE recommendations for non‐orally administered drug products including long‐acting injectables (LAI), orally inhaled drug products, and drugs applied locally to the skin ...
Steven G. Chopski +6 more
wiley +1 more source
Brazilian Journal of Otorhinolaryngology, 2022 Introduction: The effect of the quantity of olfactory neuroepithelium in the middle turbinate on the postoperative olfactory function for middle turbinate concha bullosa patients has not yet been evaluated. Objective: The primary aim of this study was to
Onur İsmi +6 more
doaj
Secretome of Olfactory Mucosa Mesenchymal Stem Cell, a Multiple Potential Stem Cell
Stem Cells International, 2016 Nasal olfactory mucosa mesenchymal stem cells (OM-MSCs) have the ability to promote regeneration in the nervous system in vivo. Moreover, with view to the potential for clinical application, OM-MSCs have the advantage of being easily accessible from ...
Lite Ge +11 more
semanticscholar +1 more source
Sensory Neuroscience, EarlyView.Sweeteners in aerosol form trigger retro‐nasal sensations that modulate early (P1) and late (P3) brain responses. EEG recordings reveal that sucrose and rebaudioside A elicit distinct ERP components only when retro‐nasal airflow is permitted, supporting aerosol‐based taste–smell integration and suggesting involvement of both top‐down and bottom‐up ...
Yue He +4 more
wiley +1 more source
Small, EarlyView.Intranasal delivery of acyl‐ghrelin using gold nanorods (AuNRs) is investigated as a strategy for treating neurodegenerative diseases. Acyl‐ghrelin is conjugated to AuNRs under optimized conditions that preserve its bioactivity and prevent nanoparticle cross‐linking.
Shunping Han +6 more
wiley +1 more source
Assessment of endoscopic and external approaches for frontal sinus lesions
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.Abstract Objectives The use of endoscopic approaches has revolutionized the management of frontal sinus (FS) lesions. However, external approaches still play a significant role in select conditions. Various factors determine the decision to utilize endoscopic or external approaches such as the lesion location, extension, and patient's characteristics ...
Moataz D. Abouammo +5 more
wiley +1 more source
Isolation of putative stem cells present in human adult olfactory mucosa
PLoS ONE, 2017 The olfactory mucosa (OM) has the unique characteristic of performing an almost continuous and lifelong neurogenesis in response to external injuries, due to the presence of olfactory stem cells that guarantee the maintenance of the olfactory function ...
T. Tanos +5 more
semanticscholar +1 more source
Living With Chronic Rhinosinusitis: Insights From an Arts‐Based Study
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Chronic rhinosinusitis (CRS) significantly reduces quality of life (QoL), but data regarding the extent of its impact is sparse. Questionnaire‐based assessments of QoL may neglect aspects of complex patient experiences. Recent studies on asthma patients and other chronic conditions have used self‐expression through artwork to better
Jenny Xiao +4 more
wiley +1 more source
Particle and Fibre Toxicology, 2019 Background Airborne pollution, especially from diesel exhaust (DE), is known to have a negative effect on the central nervous system in exposed human populations.
Estefanía Bernal-Meléndez +14 more
doaj +1 more source
Electrophysiological evidence for a topographical projection of the nasal mucosa onto the olfactory bulb of the frog. [PDF]
, 1976 Richard M. Costanzo, Maxwell M. Mozell
openalex +1 more source