Results 31 to 40 of about 447,033 (267)

Alpha-synuclein seeds in olfactory mucosa of patients with isolated REM sleep behaviour disorder.

Brain : a journal of neurology, 2021
Isolated REM sleep behaviour disorder (RBD) is an early-stage α-synucleinopathy in most, if not all, affected subjects. Detection of pathological α-synuclein in peripheral tissues of patients with isolated RBD may identify those progressing to Parkinson ...
A. Stefani, Á. Iranzo, E. Holzknecht, D. Perra, M. Bongianni, C. Gaig, B. Heim, M. Serradell, Luca Sacchetto, Alicia Garrido, S. Capaldi, A. Sánchez-Gómez, M. P. Cecchini, S. Mariotto, S. Ferrari, M. Fiorini, J. Schmutzhard, P. Cocchiara, I. Vilaseca, Lorenzo Brozzetti, S. Monaco, M. José Martí, K. Seppi, E. Tolosa, J. Santamaria, B. Högl, W. Poewe, G. Zanusso   +27 more
semanticscholar   +1 more source

Isolation and Characterization of Cat Olfactory Ecto-Mesenchymal Stem Cells

Animals, 2022
The olfactory mucosa contains olfactory ecto-mesenchymal stem cells (OE-MSCs) which show stemness features, multipotency capabilities, and have a therapeutic potential. The OE-MSCs have already been collected and isolated from various mammals. The aim of
Marie-Laure Mollichella, Violaine Mechin, Dany Royer, Patrick Pageat, Pietro Asproni   +4 more
doaj   +1 more source

Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo

Stem Cells International, 2021
Peripheral nerve injury remains a clinical challenge with severe physiological and functional consequences. Despite the existence of multiple possible therapeutic approaches, until now, there is no consensus regarding the advantages of each option or the
R. Alvites, M. Branquinho, A. Sousa, I. Amorim, R. Magalhães, F. João, Diogo Almeida, S. Amado, J. Prada, I. Pires, Federica Zen, S. Raimondo, A. Luís, S. Geuna, A. Varejão, A. Maurício   +15 more
semanticscholar   +1 more source

Histopathologic Findings of Olfactory Mucosa in COVID-19 Patients

Otorhinolaryngology and Facial Plastic Surgery, 2023
Background: Olfactory manifestations are common findings during the course of COVID-19, while exact physiopathology is not known Aim: We review histological changes of the nasal olfactory mucosa in COVID-19 non-survivors who died in the ICU ...
Jahangir Ghorbani, Mahin Pourabdollah, Nasim Raad, Mahboobeh Karimi Galougahi, Atefeh Abedini, Behrooz Farzanegan, Seyed Mohammadreza Hashemian, Seyed Alireza Nadji, Amirali Safavi Naini, Ali Safavi Naini   +9 more
doaj   +1 more source

Impact of Copper Nanoparticles and Copper Ions on Transcripts Involved in Neural Repair Mechanisms in Rainbow Trout Olfactory Mucosa

Archives of Environmental Contamination and Toxicology, 2022
Olfactory mucosa is well known for its lifelong ability for regeneration. Regeneration of neurons and regrowth of severed axons are the most common neural repair mechanisms in olfactory mucosa.
P. Razmara, G. Pyle
semanticscholar   +1 more source

Olfactory ensheathing cells in facial nerve regeneration

Brazilian Journal of Otorhinolaryngology, 2020
Introduction: Olfactory ensheathing cell is a unique kind of glia cells, which can promote axon growth. Little is known about the differences between olfactory mucosa olfactory ensheathing cells and olfactory bulb olfactory ensheathing cells in the ...
Manyi Li, Qiubei Zhu, Jisheng Liu
doaj   +1 more source

Zika virus leads to olfactory disorders in mice by targeting olfactory ensheathing cellsResearch in context

EBioMedicine, 2023
Summary: Background: Zika virus (ZIKV) is an emerging arbovirus of the genus flavivirus that is associated with congenital Zika syndrome (CZS) in newborns.
Jia Zhou, Meng-Yue Guan, Rui-Ting Li, Yi-Ni Qi, Guan Yang, Yong-Qiang Deng, Xiao-Feng Li, Liang Li, Xiao Yang, Jian-Feng Liu, Cheng-Feng Qin   +10 more
doaj   +1 more source

Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. [PDF]

PLoS ONE, 2017
Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfactory nerves. We have previously demonstrated that the cribriform plate is permissive for T cells and monocytes and that viruses can enter the bulb upon ...
Carolin Piotrowski, Vera Lede, Anne Butthof, Nicole Kaiser, Petra G Hirrlinger, Matthias H Tschöp, Torsten Schöneberg, Ingo Bechmann   +7 more
doaj   +1 more source

Fibroblasts isolated from human middle turbinate mucosa cause neural progenitor cells to differentiate into glial lineage cells. [PDF]

PLoS ONE, 2013
Transplantation of olfactory ensheathing cells (OECs) is a potential therapy for repair of spinal cord injury (SCI). Autologous transplantation of OECs has been reported in clinical trials.
Xingjia Wu, William E Bolger, Juanita J Anders   +2 more
doaj   +1 more source

Lesion of the olfactory epithelium accelerates prion neuroinvasion and disease onset when prion replication is restricted to neurons. [PDF]

PLoS ONE, 2015
Natural prion diseases of ruminants are moderately contagious and while the gastrointestinal tract is the primary site of prion agent entry, other mucosae may be entry sites in a subset of infections.
Jenna Crowell, James A Wiley, Richard A Bessen   +2 more
doaj   +1 more source