Results 21 to 30 of about 447,033 (267)
Nano-in-Micro-Particles Consisting of PLGA Nanoparticles Embedded in Chitosan Microparticles via Spray-Drying Enhances Their Uptake in the Olfactory Mucosa. [PDF]
Front Pharmacol, 2021 Intranasal delivery has gained prominence since 1990, when the olfactory mucosa was recognized as the window to the brain and the central nervous system (CNS); this has enabled the direct site specific targeting of neurological diseases for the first ...
Spindler LM +9 more
europepmc +2 more sources
Office‐based olfactory mucosa biopsies [PDF]
International Forum of Allergy & Rhinology, 2016 BackgroundRequests from researchers for olfactory mucosal biopsies are increasing as a result of advances in the fields of neuroscience and stem cell biology. Published studies report variable rates of success in obtaining true olfactory tissue, often below 50%.
E. Holbrook, Lina Rebeiz, J. Schwob
semanticscholar +3 more sources
Differentiation of human olfactory mucosa mesenchymal stem cells into photoreceptor cells in vitro [PDF]
International Journal of Ophthalmology, 2017 AIM: To investigate whether the human olfactory mucosa mesenchymal stem cells (OM-MSCs) can differentiate into photoreceptor cells in vitro. METHODS: Through the olfactory mucosa adherent method, olfactory mucosa was isolated, cultured and identified in
Wen Lu +4 more
doaj +2 more sources
Olfactory Ensheathing Cell Tumor Arising from the Olfactory Mucosa [PDF]
Case Reports in Medicine, 2012 We report a rare case of olfactory ensheathing cell tumor. A female presented a large soft mass extending medially to the olfactory cleft and laterally to the middle meatus in the left nasal cavity.
Eriko Ogino-Nishimura +3 more
doaj +4 more sources
Environmental toxicants-induced immune responses in the olfactory mucosa
Frontiers in Immunology, 2016 Olfactory sensory neurons (OSNs) are the receptor cells for the sense of smell. Although cell bodies are located in the olfactory mucosa of the nasal cavity, OSN axons directly project to the olfactory bulb that is a component of the central nervous ...
Fumiaki Imamura, Sanae Hasegawa-Ishii
doaj +2 more sources
Oxidative Chemical Stressors Alter the Physiological State of the Nasal Olfactory Mucosa of Atlantic Salmon. [PDF]
Antioxidants (Basel), 2020 The olfactory organs of fish have vital functions for chemosensory and defence. Though there have been some ground-breaking discoveries of their involvement in immunity against pathogens in recent years, little is known about how they respond to non ...
Lazado CC +5 more
europepmc +2 more sources
Endothelin increases the proliferation of rat olfactory mucosa cells
Neural Regeneration Research, 2020 The olfactory mucosa holds olfactory sensory neurons directly in contact with an aggressive environment. In order to maintain its integrity, it is one of the few neural zones which are continuously renewed during the whole animal life.
Bertrand Bryche +5 more
doaj +2 more sources
Multipotent stem cells from adult olfactory mucosa [PDF]
Developmental Dynamics, 2005 AbstractMultipotent stem cells are thought to be responsible for the generation of new neurons in the adult brain. Neurogenesis also occurs in an accessible part of the nervous system, the olfactory mucosa. We show here that cells from human olfactory mucosa generate neurospheres that are multipotent in vitro and when transplanted into the chicken ...
Murrell, W +9 more
openaire +6 more sources
Pharmaceutics, 2018 The blood-brain barrier and the blood-cerebrospinal fluid barrier are major obstacles in central nervous system (CNS) drug delivery, since they block most molecules from entering the brain.
Stella Gänger, K. Schindowski
semanticscholar +3 more sources
Frontiers in Aging Neuroscience, 2018 Background: The incidence of olfactory impairment increases with age; however, the detailed molecular and cellular mechanisms underlying this increase are yet to be determined.Methods: We examined the influence of aging on olfactory receptor neurons ...
Rumi Ueha +7 more
doaj +2 more sources