Results 11 to 20 of about 16,659 (194)

Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. [PDF]

PLoS ONE, 2017
Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfactory nerves. We have previously demonstrated that the cribriform plate is permissive for T cells and monocytes and that viruses can enter the bulb upon ...
Carolin Piotrowski, Vera Lede, Anne Butthof, Nicole Kaiser, Petra G Hirrlinger, Matthias H Tschöp, Torsten Schöneberg, Ingo Bechmann   +7 more
doaj   +1 more source

Secreted factors from olfactory mucosa cells expanded as free-floating spheres increase neurogenesis in olfactory bulb neurosphere cultures

BMC Neuroscience, 2008
Background The olfactory epithelium is a neurogenic tissue comprising a population of olfactory receptor neurons that are renewed throughout adulthood by a population of stem and progenitor cells. Because of their relative accessibility compared to intra-
Caldwell Maeve A, He Xiaoling, Barraud Perrine, Franklin Robin JM   +3 more
doaj   +1 more source

Fibroblasts isolated from human middle turbinate mucosa cause neural progenitor cells to differentiate into glial lineage cells. [PDF]

PLoS ONE, 2013
Transplantation of olfactory ensheathing cells (OECs) is a potential therapy for repair of spinal cord injury (SCI). Autologous transplantation of OECs has been reported in clinical trials.
Xingjia Wu, William E Bolger, Juanita J Anders   +2 more
doaj   +1 more source

HISTOCHEMICAL STUDIES OF THE OLFACTORY MUCOSA OF THE RABBIT [PDF]

Journal of Histochemistry & Cytochemistry, 1955
1. Tests of the olfactory mucosa of rabbits by five different methods indicate that cholinesterase is probably not present in any of the cells of this tissue. 2. Alkaline phosphatase and phosphamidase were not found in the olfactory receptors. 3.
B J, BURKHARDT, H C, EHRMANTRAUT
openaire   +2 more sources

Lesion of the olfactory epithelium accelerates prion neuroinvasion and disease onset when prion replication is restricted to neurons. [PDF]

PLoS ONE, 2015
Natural prion diseases of ruminants are moderately contagious and while the gastrointestinal tract is the primary site of prion agent entry, other mucosae may be entry sites in a subset of infections.
Jenna Crowell, James A Wiley, Richard A Bessen   +2 more
doaj   +1 more source

Environmental toxicants-induced immune responses in the olfactory mucosa

Frontiers in Immunology, 2016
Olfactory sensory neurons (OSNs) are the receptor cells for the sense of smell. Although cell bodies are located in the olfactory mucosa of the nasal cavity, OSN axons directly project to the olfactory bulb that is a component of the central nervous ...
Fumiaki Imamura, Sanae Hasegawa-Ishii
doaj   +1 more source

Lipocalin 15 in the olfactory mucus is a biomarker for Bowman’s gland activity

Scientific Reports, 2022
Olfactory mucus contributes to the specific functions of the olfactory mucosa, but the composition and source of mucus proteins have not been fully elucidated.
Chiori Ijichi, Kenji Kondo, Masayoshi Kobayashi, Ayaka Shirasawa, Kazutaka Shimbo, Kunio Nakata, Yutaka Maruyama, Yusuke Ihara, Yayoi Kawato, Teruhisa Mannen, Rie Takeshita, Yoshimi Kikuchi, Yuki Saito, Tatsuya Yamasoba   +13 more
doaj   +1 more source

Neuropathology of the Olfactory Mucosa in Chronic Rhinosinusitis [PDF]

American Journal of Rhinology & Allergy, 2010
Background Chronic rhinosinusitis (CRS) is a complex heterogeneous inflammatory disease that affects the nasal cavity, but the pathological examination of the olfactory mucosa (OM) in this disease has been limited. Methods Nasal biopsy
Karen K, Yee, Edmund A, Pribitkin, Beverly J, Cowart, Aldona A, Vainius, Christopher T, Klock, David, Rosen, Pu, Feng, Judith, McLean, Chang-Gyu, Hahn, Nancy E, Rawson   +9 more
openaire   +2 more sources

Serum-Free Medium Provides a Clinically Relevant Method to Increase Olfactory Ensheathing Cell Numbers in Olfactory Mucosa Cell Culture

Cell Transplantation, 2007
There is much evidence to suggest that transplanted olfactory ensheathing cells may ameliorate the functional deficits associated with injuries to the nervous system, especially the spinal cord.
Daisuke Ito, Naoki Fujita, Chrystelle Ibanez, Nobuo Sasaki, Robin J. M. Franklin, Nick D. Jeffery   +5 more
doaj   +1 more source

Cytokines and olfactory bulb microglia in response to bacterial challenge in the compromised primary olfactory pathway

Journal of Neuroinflammation, 2012
Background The primary olfactory pathway is a potential route through which microorganisms from the periphery could potentially access the central nervous system.
Herbert Rosalind P, Harris Julie, Chong Kim, Chapman Jamie, West Adrian K, Chuah Meng   +5 more
doaj   +1 more source