Results 241 to 250 of about 828,914 (331)

In vivo and in silico models of Drosophila for Parkinson's disease

The FEBS Journal, EarlyView.
In vivo and in silico models of Drosophila offer valuable advantages in the generation, analysis, and interpretation of complex biological data, thereby significantly advancing our understanding of Parkinson's disease. Molecular‐level measurements and phenotypic data from Drosophila are extensively utilised in metabolic network modeling and artificial ...
Müberra Fatma Cesur, Rachel Strazdins, Souvarish Sarkar, Tunahan Çakır   +3 more
wiley   +1 more source

Neocortical neurogenesis: a proneural gene perspective

The FEBS Journal, EarlyView.
The neocortex is a mammalian‐specific brain region responsible for higher‐order cognitive functioning that shares fundamental similarities across species, but which is larger and more complex in humans. Proneural genes, encoding basic helix–loop–helix transcription factors (TFs), are evolutionarily conserved drivers of neurogenesis from fly to human ...
Lakshmy Vasan, Alexandra Moffat, Pierre Mattar, Carol Schuurmans   +3 more
wiley   +1 more source

An unexpected insight into the cause of olfactory dysfunction: fibrillogenesis of odorant-binding proteins. [PDF]

Cell Death Discov
Stepanenko OV, Sulatsky MI, Sulatskaya AI, Stepanenko OV.   +3 more
europepmc   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

Past research and future directions in understanding how birds use their sense of smell

Ibis, EarlyView.
Our understanding of the functional importance of olfaction to birds has improved over the past 60 years, largely as the result of experimental studies testing how birds use their sense of smell in different contexts. As it is impossible to measure directly which odours birds can detect, we rely on measuring behavioural responses to scent cues or ...
Darcy Creece, Rafael Freire, Melanie Massaro   +2 more
wiley   +1 more source

Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics

International Endodontic Journal, EarlyView.
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk, Ceren Turan Gökduman, Burhan Can Çanakçi   +2 more
wiley   +1 more source

The 4 item Concise Aging adults Smell Test (4CAST) to screen for olfactory-related comorbidities. [PDF]

Rhinology
Schlosser RJ, Gregoski MJ, Eckert MA, Benitez A, Soler ZM.   +4 more
europepmc   +1 more source

Cognitive and behavioral response of mosquitofish (Gambusia affinis) to environmental factors: Microplastics, predator cues, and detour design methods

Journal of Fish Biology, EarlyView.
Abstract Urban stream syndrome is the collective term used to describe the physical and ecological degradation of streams draining urban lands that poses substantial threats to freshwater ecosystems. Among various consequences of urban expansion, microplastic pollution and shifts in predator–prey dynamics are prominent alterations to natural habitat ...
Kyndal Irwin, Grace Hathorn, Caitlin R. Gabor   +2 more
wiley   +1 more source

Gustatory and olfactory-guided responsiveness to maltodextrin solutions in mice. [PDF]

Am J Physiol Regul Integr Comp Physiol
Hamel EA, Blonde GD, Williams E, Dewan A, Spector AC.   +4 more
europepmc   +1 more source

Assessing the intraspecific osteological variation of the spottail shiner (Hudsonius hudsonius) (Cypriniformes: Leuciscidae)

Journal of Fish Biology, EarlyView.
Abstract Hudsonius hudsonius (Cypriniformes: Leuciscidae), commonly known as the spottail shiner, is a small cyprinoid fish species found across much of North America. H. hudsonius has traditionally been regarded as one of the most basal and plesiomorphic species among the notropin fishes, that is, fishes traditionally placed in or associated with the ...
Erika K. Jessen
wiley   +1 more source