Results 91 to 100 of about 1,599,645 (340)

Exploring the interplay between olfaction and vision: neuroplasticity, rehabilitation, and the therapeutic potential of herbal ingredients

BMC Complementary Medicine and Therapies
Post-COVID-19, olfactory and visual training have demonstrated health benefits, particularly for individuals with visual impairments and neurodegenerative conditions such as Parkinson’s and glaucoma. Integrating olfactory training with essential oils and
Tibor Rák, Edit Ormai, Edina Pandur, Györgyi Horváth, Csutak Adrienne   +4 more
doaj   +1 more source

Insights about the Olfactory Bulb Structural organization and dysfunction [PDF]

Arcades of Medicine
The olfactory bulb (OB) is a critical structure for the sense of olfaction, processing olfactory information from the nose to the brain. The OB's is characterized by layered organization that facilitates olfactory processing.
Mostafa Daboos, Nevine Soliman, Samaa Kamar, Lobna Elkhateb   +3 more
doaj   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Host location in a specialist parasitoid wasp via olfactory cues – a physiological, behavioural and morphological study

, 2012
For successful host location, parasitoids are thought to have evolved different strategies to filter relevant olfactory cues which indicate the presence of the host. Because of their versatility in their ecology and behaviour, as well as their fine tuned
Groll, Helga
core   +1 more source

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

A Quantitative Model for Human Olfactory Receptors [PDF]

, 2012
A wide variety of chemicals having distinct odors are smelled by humans. Odor perception initiates in the nose, where it is detected by a large family of olfactory receptors (ORs).
Sk. Sarif Hassan, Pabitra Pal Choudhury, Aritra Bose   +2 more
core   +1 more source

What's that smell? A pictorial review of the olfactory pathways and imaging assessment of the myriad pathologies that can affect them. [PDF]

Insights Imaging, 2021
Lie G, Wilson A, Campion T, Adams A.
europepmc   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source

Cortex- and striatum-derived neural stem cells produce distinct progeny in the olfactory bulb and striatum [PDF]

, 2008
Neural stem cells can be isolated from the mouse embryonic cortex but do not persist in the adult cortex. In contrast, neural stem cells from the striatal embryonic germinal zone persist in the adult subependyma.
Willaime-Morawek, S., Van der Kooy, D.
core   +1 more source

Tau propagation in the brain olfactory circuits is associated with smell perception changes in aging

Nature Communications
The direct access of olfactory afferents to memory-related cortical systems has inspired theories about the role of the olfactory pathways in the development of cortical neurodegeneration in Alzheimer’s disease (AD).
Ibai Diez, Laura Ortiz-Terán, Thomas S. C. Ng, Mark W. Albers, Gad Marshall, William Orwig, Chan-mi Kim, Elisenda Bueichekú, Victor Montal, Jonas Olofsson, Patrizia Vannini, Georges El Fahkri, Reisa Sperling, Keith Johnson, Heidi I. L. Jacobs, Jorge Sepulcre   +15 more
doaj   +1 more source