Results 81 to 90 of about 134,738 (304)
Harnessing the power of cell transplantation to target respiratory dysfunction following spinal cord injury. [PDF]
, 2017 The therapeutic benefit of cell transplantation has been assessed in a host of central nervous system (CNS) diseases, including disorders of the spinal cord such as traumatic spinal cord injury (SCI).
Charsar, Brittany A. +2 more
core +2 more sources
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Competence, specification and commitment to an olfactory placode fate [PDF]
, 2008 The nasal placode shares a common origin with other sensory placodes within a pre-placodal domain at the cranial neural plate border. However, little is known about early events in nasal placode development as it segregates from prospective lens, neural ...
Bhattacharyya, Sujata +1 more
core +2 more sources
Advanced Science, EarlyView.This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li +7 more
wiley +1 more source
Frontiers in NeuroscienceOlfactory dysfunction has emerged as a hallmark feature shared among several neurological conditions, including both neurodevelopmental and neurodegenerative disorders.
Yu-Nan Chen, Johanna Katharina Kostka
doaj +1 more source
Dual olfactory pathway in the honeybee, Apis mellifera [PDF]
Journal of Comparative Neurology, 2006 AbstractThe antennal lobes (ALs) are the primary olfactory centers in the insect brain. In the AL of the honeybee, olfactory glomeruli receive input via four antennal sensory tracts (T1–4). Axons of projection neurons (PNs) leave the AL via several antenno‐cerebral tracts (ACTs). To assign the input–output connectivity of all glomeruli, we investigated
Kirschner, Sebastian +5 more
openaire +6 more sources
Advanced Science, EarlyView.Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
Hendra and Nipah Virus Infection in Cultured Human Olfactory Epithelial Cells
mSphere, 2017 Henipaviruses are emerging zoonotic viruses and causative agents of encephalitis in humans. However, the mechanisms of entry into the central nervous system (CNS) in humans are not known.
Viktoriya Borisevich +3 more
doaj +1 more source
Subpopulations of Projection Neurons in the Olfactory Bulb
Frontiers in Neural Circuits, 2020 Generation of neuronal diversity is a biological strategy widely used in the brain to process complex information. The olfactory bulb is the first relay station of olfactory information in the vertebrate central nervous system.
Fumiaki Imamura +2 more
doaj +1 more source
Oral Inflammation, Tooth Loss, Risk Factors, and Association with Progression of Alzheimer’s Disease [PDF]
, 2014 Periodontitis is a polymicrobial chronic inflammatory disease of tooth-supporting tissues with bacterial etiology affecting all age groups, becoming chronic in a subgroup of older individuals.
Crean, Stjohn +5 more
core +1 more source