Results 91 to 100 of about 2,532,098 (296)

Alzheimer’s Disease: What Can We Learn From the Peripheral Olfactory System?

Frontiers in Neuroscience, 2020
The sense of smell has been shown to deteriorate in patients with some neurodegenerative disorders. In Parkinson’s disease (PD) and Alzheimer’s disease (AD), decreased ability to smell is associated with early disease stages.
Michele Dibattista, Simone Pifferi, Anna Menini, Johannes Reisert   +3 more
doaj   +1 more source

Co-regulation of a large and rapidly evolving repertoire of odorant receptor genes

BMC Neuroscience, 2007
The olfactory system meets niche- and species-specific demands by an accelerated evolution of its odorant receptor repertoires. In this review, we describe evolutionary processes that have shaped olfactory and vomeronasal receptor gene families in ...
Lane Robert P, Kambere Marijo B
doaj   +1 more source

The Olfactory Nervous System Of Terrestrial And Aquatic Vertebrates [PDF]

, 2011
Animals in their natural milieu are surrounded by odors. These odors are rich source of information, and are perceived by sophisticated olfactory systems, that have evolved over time.
Ashiq Hussain
core   +1 more source

Olfactory modulation of flight in Drosophila is sensitive, selective and rapid [PDF]

, 2010
Freely flying Drosophila melanogaster respond to odors by increasing their flight speed and turning upwind. Both these flight behaviors can be recapitulated in a tethered fly, which permits the odor stimulus to be precisely controlled.
Ashburner, Bender, Bender, Berry, Bhandawat, Borst, Budick, Budick, Carlson, Chow, Collett, de Bruyne, de Bruyne, Dickinson, Duistermars, Duistermars, Duistermars, Fiala, Frye, Frye, Goldman, Gopfert, Guo, Götz, Hallem, Heide, Heide, Holmes, Kaissling, Kazama, Land, Larsson, Lehmann, Levine, Luo, Manning, Olsen, Olsen, Olsen, Rospars, Semmelhack, Stocker, Tammero, Wilson, Wolf, Xi, Yorozu, Zhu   +47 more
core   +3 more sources

Ultramicroscopic organization of the exterior olfactory organ in Anguilla vulgaris in relation to its spawning migration

Open Veterinary Journal
Background: Catadromous fishes have well developed elongate olfactory organs with numerous lamellae and different types of receptor neurons related to their breeding migration.
Sheren A. Al-Zahaby, Sahar S. Hassan, Eman H. Elsheikh   +2 more
doaj   +1 more source

Olfactory function in the trace amine-associated receptor family (TAARs) evolved twice independently

Scientific Reports, 2021
Olfactory receptor families have arisen independently several times during evolution. The origin of taar genes, one of the four major vertebrate olfactory receptor families, is disputed.
Milan Dieris, Daniel Kowatschew, Sigrun I. Korsching   +2 more
doaj   +1 more source

Identification of novel post-transcriptional features in olfactory receptor family mRNAs. [PDF]

, 2015
Olfactory receptor (Olfr) genes comprise the largest gene family in mice. Despite their importance in olfaction, how most Olfr mRNAs are regulated remains unexplored.
Espinoza, Josh L, Ramaiah, Madhuvanthi, Shum, Eleen Y, Wilkinson, Miles F   +3 more
core   +1 more source

Resolving different presynaptic activity patterns within single olfactory glomeruli of Xenopus laevis larvae

Scientific Reports, 2021
Olfactory sensing is generally organized into groups of similarly sensing olfactory receptor neurons converging into their corresponding glomerulus, which is thought to behave as a uniform functional unit.
Rodi Topci, Mihai Alevra, Erik H. U. Rauf, Daniëlle de Jong-Bolm   +3 more
doaj   +1 more source

Insertion of T4-lysozyme (T4L) can be a useful tool for studying olfactory-related GPCRs. [PDF]

, 2012
The detergents used to solubilize GPCRs can make crystal growth the rate-limiting step in determining their structure. The Kobilka laboratory showed that insertion of T4-lysozyme (T4L) in the 3rd intracellular loop is a promising strategy towards ...
Baaske, Baud, Brian L. Cook, Cherezov, Chien, Christoph J. Wienken, Cook, Cook, Corin, Corin, Dahoun, Dieter Braun, Duhr, Garavito, Gimelbrant, Gimelbrant, Greenfield, Hanson, Horst Pick, Horst Vogel, Jaakola, Jacquier, Jayadev, Karolina Corin, Katada, Loll, Lu, Lu, McClintock, Philipp Baaske, Pick, Rasmussen, Ren, Rodriguez, Shimamura, Shirokova, Shuguang Zhang, Spehr, Spehr, Stefan Duhr, Wallin, Warne, Wienken, Wu   +43 more
core   +1 more source

Olfactory receptor antagonism between odorants [PDF]

The EMBO Journal, 2003
The detection of thousands of volatile odorants is mediated by several hundreds of different G protein-coupled olfactory receptors (ORs). The main strategy in encoding odorant identities is a combinatorial receptor code scheme in that different odorants are recognized by different sets of ORs.
Oka, Yuki, Omura, Masayo, Kataoka, Hiroshi, Touhara, Kazushige   +3 more
openaire   +3 more sources