Results 121 to 130 of about 263,442 (328)

Evaluation of projection patterns in the primary olfactory system of rainbow trout [PDF]

, 1991
DR Riddle, Bruce Oakley
openalex   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Odors: from chemical structures to gaseous plumes [PDF]

, 2020
We are immersed within an odorous sea of chemical currents that we parse into individual odors with complex structures. Odors have been posited as determined by the structural relation between the molecules that compose the chemical compounds and their ...
Escalon, James A., Mathew, Dennis, Young, Benjamin D.   +2 more
core  

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Association between olfactory sulcus morphology and olfactory functioning in schizophrenia and psychosis high-risk status

Heliyon, 2019
Olfactory impairment has been reported in patients with schizophrenia and individuals with a high risk of psychosis, but its neural basis is largely unknown.
Tsutomu Takahashi, Mihoko Nakamura, Daiki Sasabayashi, Yumiko Nishikawa, Yoichiro Takayanagi, Atsushi Furuichi, Mikio Kido, Yuko Mizukami, Shimako Nishiyama, Yuko Higuchi, Takahiro Tateno, Hiroko Itoh, Kyo Noguchi, Yuri Masaoka, Michio Suzuki   +14 more
doaj   +1 more source

Peer Review #3 of "Avoidance of copper by fathead minnows (Pimephales promelas) requires an intact olfactory system (v0.1)"

, 2022

openalex   +1 more source

SAGE: Spatially Aware Gene Selection and Dual‐View Embedding Fusion for Domain Identification in Spatial Transcriptomics

Advanced Science, EarlyView.
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He, Yunpei Xu, Liqing Ding, Hong‐Dong Li, Yaohang Li, Shaokai Wang   +5 more
wiley   +1 more source

Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as Neural Signaling Molecules [PDF]

, 2008
The definitive version is available at www3.interscience.wiley ...
Cravatt, BF, Egertova, M, Elphick, MR, Simon, GM   +3 more
core  

Reconstructing Coherent Functional Landscape From Multi‐Modal Multi‐Slice Spatial Transcriptomics by a Variational Spatial Gaussian Process

Advanced Science, EarlyView.
This study introduces stVGP, a variational spatial Gaussian process framework for multi‐modal, multi‐slice spatial transcriptomics. By integrating histological and genomic data through hybrid alignment and attention‐based fusion, stVGP reconstructs coherent 3D functional landscapes.
Zedong Wang, Bowen Fu, Chuanchao Zhang, Xiaoping Liu   +3 more
wiley   +1 more source

Orientation through chemo reception in fishes [PDF]

A system designed to acquire and process data describing locomotor behavior of fish is described. Data are recorded in relation to the fish's response to olfactory stimuli.
Kleerekoper, H.
core   +1 more source