Results 41 to 50 of about 116,389 (210)

Development of a noninvasive olfactory stimulation fMRI system in marmosets

Scientific Reports
Olfactory dysfunction is associated with aging and the earliest stages of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases; it is thought to be an early biomarker of cognitive decline. In marmosets, a small non-human primate model
Terumi Yurimoto, Fumiko Seki, Akihiro Yamada, Junnosuke Okajima, Tomoyuki Yambe, Yoshiaki Takewa, Michiko Kamioka, Takashi Inoue, Yusuke Inoue, Erika Sasaki   +9 more
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Zika virus leads to olfactory disorders in mice by targeting olfactory ensheathing cellsResearch in context

EBioMedicine, 2023
Summary: Background: Zika virus (ZIKV) is an emerging arbovirus of the genus flavivirus that is associated with congenital Zika syndrome (CZS) in newborns.
Jia Zhou, Meng-Yue Guan, Rui-Ting Li, Yi-Ni Qi, Guan Yang, Yong-Qiang Deng, Xiao-Feng Li, Liang Li, Xiao Yang, Jian-Feng Liu, Cheng-Feng Qin   +10 more
doaj  

3D standard brain of the red flour beetle Tribolium castaneum: a tool to study metamorphic development and adult plasticity

Frontiers in Systems Neuroscience, 2010
The red flour beetle Tribolium castaneum is emerging as a further standard insect model beside Drosophila. Its genome is fully sequenced and it is susceptible for genetic manipulations including RNA-interference.
David Dreyer, David Dreyer, Holger Vitt, Stefan Dippel, Stefan Dippel, Brigitte Goetz, Basil El Jundi, Martin Kollmann, Wolf Huetteroth, Wolf Huetteroth, Joachim Schachtner   +10 more
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Nasal Administration of Cholera Toxin as a Mucosal Adjuvant Damages the Olfactory System in Mice. [PDF]

PLoS ONE, 2015
Cholera toxin (CT) induces severe diarrhea in humans but acts as an adjuvant to enhance immune responses to vaccines when administered orally. Nasally administered CT also acts as an adjuvant, but CT and CT derivatives, including the B subunit of CT (CTB)
Yoshiko Fukuyama, Kazunari Okada, Masahiro Yamaguchi, Hiroshi Kiyono, Kensaku Mori, Yoshikazu Yuki   +5 more
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Olfactory Evaluation in Alzheimer’s Disease Model Mice

Brain Sciences, 2022
Olfactory dysfunction is considered a pre-cognitive biomarker of Alzheimer’s disease (AD). Because the olfactory system is highly conserved across species, mouse models corresponding to various AD etiologies have been bred and used in numerous studies on
Jingjing Zhang, Zixuan Zhao, Siqi Sun, Jing Li, Yu Wang, Jingyin Dong, Su Yang, Yiyi Lou, Jing Yang, Weiyun Li, Shanshan Li   +10 more
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Nasal Placode Development, GnRH Neuronal Migration and Kallmann Syndrome

Frontiers in Cell and Developmental Biology, 2019
The development of Gonadotropin releasing hormone-1 (GnRH) neurons is important for a functional reproduction system in vertebrates. Disruption of GnRH results in hypogonadism and if accompanied by anosmia is termed Kallmann Syndrome (KS).
Hyun-Ju Cho, Yufei Shan, Niteace C. Whittington, Susan Wray   +3 more
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Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in Drosophila

eLife, 2018
Loss of the sense of smell is among the first signs of natural aging and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Cellular and molecular mechanisms promoting this smell loss are not understood.
Ashiq Hussain, Atefeh Pooryasin, Mo Zhang, Laura F Loschek, Marco La Fortezza, Anja B Friedrich, Catherine-Marie Blais, Habibe K Üçpunar, Vicente A Yépez, Martin Lehmann, Nicolas Gompel, Julien Gagneur, Stephan J Sigrist, Ilona C Grunwald Kadow   +13 more
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Odorant Receptors Signaling Instructs the Development and Plasticity of the Glomerular Map

Neural Plasticity, 2015
The olfactory system provides a great opportunity to explore the mechanisms that underlie the formation and function of neural circuits because of the simplicity of its structure.
Pablo Valle-Leija
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Analyzing the structure and function of neuronal circuits in zebrafish

Frontiers in Neural Circuits, 2013
The clever choice of animal models has been instrumental for many breakthrough discoveries in life sciences. One of the outstanding challenges in neuroscience is the in-depth analysis of neuronal circuits to understand how interactions between large ...
Rainer eFriedrich, Christel eGenoud, Adrian A Wanner   +2 more
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Functional units in the olfactory system [PDF]

Proceedings of the National Academy of Sciences, 2006
At each stage of odor coding, the olfactory system is divided into anatomical subdivisions that seem to serve distinct functions. Although the olfactory (piriform) cortex has long been known to have anterior and posterior subdivisions with different local architectures (1), the function of these anatomical units has been poorly understood.
Brett C. Johnson, Michael Leon
openaire   +3 more sources