Results 41 to 50 of about 263,442 (328)

Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism [PDF]

, 2004
Defects of either anosmin-1 or fibroblast growth factor receptor 1 (FGFR1) are known to underlie hereditary Kallmann's syndrome (KS), a human disorder of olfactory and gonadotropin-releasing hormone (GnRH) neuronal ontogeny.
Bouloux, PM, Gonzalez-Martinez, D, Guimond, S, Hu, YL, Kim, SH, Schofield, J, Turnbull, J, Vannelli, GB, Winyard, P   +8 more
core   +1 more source

The olfactory pathway in the peracarid crustacean Parhyale hawaiensis (Malacostraca): new insights into the evolution of olfactory processing in Pancrustacea

Open Biology
Our current understanding of the functional morphology of olfactory systems in arthropods largely relies on information obtained in hexapods. Existing analyses of the olfactory pathway in crustacean representatives have suggested that these animals share
Katja Kümmerlen, Rabea Schlüter, Steffen Harzsch   +2 more
doaj   +1 more source

Nasal Placode Development, GnRH Neuronal Migration and Kallmann Syndrome

Frontiers in Cell and Developmental Biology, 2019
The development of Gonadotropin releasing hormone-1 (GnRH) neurons is important for a functional reproduction system in vertebrates. Disruption of GnRH results in hypogonadism and if accompanied by anosmia is termed Kallmann Syndrome (KS).
Hyun-Ju Cho, Yufei Shan, Niteace C. Whittington, Susan Wray   +3 more
doaj   +1 more source

Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in Drosophila

eLife, 2018
Loss of the sense of smell is among the first signs of natural aging and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Cellular and molecular mechanisms promoting this smell loss are not understood.
Ashiq Hussain, Atefeh Pooryasin, Mo Zhang, Laura F Loschek, Marco La Fortezza, Anja B Friedrich, Catherine-Marie Blais, Habibe K Üçpunar, Vicente A Yépez, Martin Lehmann, Nicolas Gompel, Julien Gagneur, Stephan J Sigrist, Ilona C Grunwald Kadow   +13 more
doaj   +1 more source

Pheromone Sensing in Mammals: A Review of the Vomeronasal System

Anatomia, 2023
This review addresses the role of chemical communication in mammals, giving special attention to the vomeronasal system in pheromone-mediated interactions.
Mateo V. Torres, Irene Ortiz-Leal, Pablo Sanchez-Quinteiro   +2 more
doaj   +1 more source

Neuroethology of olfactory-guided behavior and its potential application in the control of harmful insects [PDF]

, 2016
Harmful insects include pests of crops and storage goods, and vectors of human and animal diseases. Throughout their history, humans have been fighting them using diverse methods.
Guerenstein, Pablo Gustavo, Lei, Hong, Reisenman, Carolina Esther   +2 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Glomerular Organization of the Antennal Lobes of the Diamondback Moth, Plutella xylostella L.

Frontiers in Neuroanatomy, 2019
The antennal lobe of the moth brain is the primary olfactory center processing information concerning pheromones and plant odors. Plutella xylostella is a major worldwide pest of cruciferous vegetables and its behavior is highly dependent on their ...
Xizhong Yan, Zhiyu Wang, Jiaoxin Xie, Caiping Deng, Xuejun Sun, Xuejun Sun, Chi Hao   +6 more
doaj   +1 more source

The role of two anatomically separate olfactory bulbs in shark food odor tracking [PDF]

, 2017
Most sharks have well-developed olfactory systems and depend to a large degree on odor information to locate food, home and navigate, and possibly detect predators and mates.
Lohe, Adrienne
core   +1 more source

Perceived synchronization of olfactory multimedia [PDF]

, 2010
This is the post-print version of this Article. The official published version can be accessed from the link below - Copyright @ 2010 IEEEThe concept of synchronization is of fundamental importance in multimedia systems and applications.
Ademoye, OA, Ghinea, G
core   +1 more source