Results 71 to 80 of about 3,502,141 (274)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb [PDF]

, 2007
The formation of precise stereotypic connections in sensory systems is critical for the ability to detect and process signals from the environment. In the olfactory system, olfactory sensory neurons (OSNs) project axons to spatially defined glomeruli ...
Cloutier, J-F, Cho, JH, Parnavelas, J, Andrews, W, Lépine, M   +4 more
core  

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Topological reorganization of odor representations in the olfactory bulb. [PDF]

, 2007
Odors are initially represented in the olfactory bulb (OB) by patterns of sensory input across the array of glomeruli. Although activated glomeruli are often widely distributed, glomeruli responding to stimuli sharing molecular features tend to be ...
Friedrich, Rainer W., Benjamin Judkewitz, Rainer W Friedrich, Judkewitz, Benjamin, Yaksi, E., Yaksi, Emre, Friedrich, Rainer W, Judkewitz, B., Friedrich, R., Emre Yaksi   +9 more
core   +2 more sources

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

The influence of olfactory training on depressive symptoms and olfactory function in patients with olfactory dysfunction – A prospective observational pilot study

Journal of Affective Disorders Reports
Introduction: Olfaction plays an important role in different aspects of our daily functioning and there is a positive correlation between olfactory dysfunction (OD) and depressive symptoms.
Emilie Keusters, Marnick Clijsters, Kristof Vansteelandt, Laura Van Gerven, Filip Bouckaert   +4 more
doaj   +1 more source

Effect of Ultra-Micronized Palmitoylethanolamide and Luteolin on Olfaction and Memory in Patients with Long COVID: Results of a Longitudinal Study

Cells, 2022
In this study, we investigated whether treatment with palmitoylethanolamide and luteolin (PEA-LUT) leads to improvement in the quantitative or qualitative measures of olfactory dysfunction or relief from mental clouding in patients affected by long COVID.
Pietro De Luca, Angelo Camaioni, Pasquale Marra, Giovanni Salzano, Giovanni Carriere, Luca Ricciardi, Resi Pucci, Nicola Montemurro, Michael J. Brenner, Arianna Di Stadio   +9 more
doaj   +1 more source

Olfactory Training

Kronenbuerger M, Pilgramm M.
europepmc   +2 more sources

Optophysiological analysis of pattern classification strategies in the zebrafish olfactory bulb [PDF]

, 2012
Classification of overlapping activity patterns is a common problem for sensory systems. For a robust representation of sensory stimuli, neuronal circuits should generalize over input patterns reflecting variations of the same stimulus but separate ...
Niessing, Jörn
core   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source