Risperidone regulates the expression of schizophrenia-related genes in the forebrain of adult male mice [PDF]
IntroductionRisperidone is a widely used antipsychotic that reduces psychotic symptoms through modulation of monoaminergic signaling. At the cellular level, however, its effects extend beyond receptor antagonism and induce spatially discrete ...
Magdalena Ziemiańska +8 more
doaj +2 more sources
Illustrated Review of the Ventral Striatum's Olfactory Tubercle. [PDF]
Modern neuroscience often relies upon artistic renderings to illustrate key aspects of anatomy. These renderings can be in 2 or even 3 dimensions. Three-dimensional renderings are especially helpful in conceptualizing highly complex aspects of neuroanatomy which otherwise are not visually apparent in 2 dimensions or even intact biological samples ...
Xiong A, Wesson DW.
europepmc +4 more sources
Embryonic and postnatal development of mouse olfactory tubercle. [PDF]
The olfactory tubercle (OT) is located in the ventral-medial region of the brain where it receives primary input from olfactory bulb (OB) projection neurons and processes olfactory behaviors related to motivation, hedonics of smell and sexual encounters.
Martin-Lopez E +4 more
europepmc +3 more sources
The Neurotransmitter Receptor Architecture of the Mouse Olfactory System
The uptake, transmission and processing of sensory olfactory information is modulated by inhibitory and excitatory receptors in the olfactory system. Previous studies have focused on the function of individual receptors in distinct brain areas, but the ...
Kimberley Lothmann +3 more
doaj +1 more source
Functional Sub-Circuits of the Olfactory System Viewed from the Olfactory Bulb and the Olfactory Tubercle. [PDF]
Understanding of the olfactory neural circuits has progressed beyond analysis of how odor information from the external environment is processed in the brain. While spatially-organized sub-circuits were found to exist up to the olfactory bulb (OB), the arrangement in the olfactory cortex (OC), especially in its representative piriform cortex (PC ...
Yamaguchi M.
europepmc +4 more sources
Heterogeneous extracellular dopamine regulation in the subregions of the olfactory tubercle. [PDF]
AbstractRecent studies show that dense dopamine (DA) innervation from the ventral tegmental area to the olfactory tubercle (OT) may play an important role in processing multisensory information pertaining to arousal and reward, yet little is known about DA regulation in the OT. This is mainly due to the anatomical limitations of conventional methods of
Park J +3 more
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The embryonic septum and ventral pallium, new sources of olfactory cortex cells. [PDF]
The mammalian olfactory cortex is a complex structure located along the rostro-caudal extension of the ventrolateral prosencephalon, which is divided into several anatomically and functionally distinct areas: the anterior olfactory nucleus, piriform ...
María Laura Ceci +2 more
doaj +1 more source
Smelling Sounds: Olfactory–Auditory Sensory Convergence in the Olfactory Tubercle [PDF]
Historical and psychophysical literature has demonstrated a perceptual interplay between olfactory and auditory stimuli—the neural mechanisms of which are not understood. Here, we report novel findings revealing that the early olfactory code is subjected to auditory cross-modal influences.In vivoextracellular recordings from the olfactory tubercle, a ...
Daniel W, Wesson, Donald A, Wilson
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Parallel odor processing by two anatomically distinct olfactory bulb target structures. [PDF]
The olfactory cortex encompasses several anatomically distinct regions each hypothesized to provide differential representation and processing of specific odors. Studies exploring whether or not the diversity of olfactory bulb input to olfactory cortices
Colleen A Payton +2 more
doaj +1 more source
The olfactory tubercle encodes odor valence in behaving mice. [PDF]
Sensory information acquires meaning to adaptively guide behaviors. Despite odors mediating a number of vital behaviors, the components of the olfactory system responsible for assigning meaning to odors remain unclear. The olfactory tubercle (OT), a ventral striatum structure that receives monosynaptic input from the olfactory bulb, is uniquely ...
Gadziola MA +3 more
europepmc +4 more sources

