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Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome. [PDF]
Makhani N +33 more
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Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German–Austrian retrospective multicenter study in patients with a clinically isolated syndrome [PDF]
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Oligoclonal bands: clinical utility and interpretation cues
Critical Reviews in Clinical Laboratory Sciences, 2022Oligoclonal immunoglobulin G (IgG) bands (OCBs) are a useful diagnostic tool to detect a central humoral response. In particular, cerebrospinal fluid (CSF)-restricted OCBs represent a hallmark of multiple sclerosis (MS), where they can be detected in > 90% of cases and support its diagnosis, although a specific causative agent inducing B cell ...
Carta, Sara +4 more
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Oligoclonal Bands in Meningeal Carcinomatosis
Archives of Neurology, 1983To the Editor. —In a recent article, Wallen et al described oligoclonal bands (OCBs) in CSF of 12 of 13 patients with African Burkitt's lymphoma with probable or definite meningeal metastases (Archives1983;40:11-13). These authors noted the possibility that the OCBs might have been synthesized by the lymphoma cells.
J R, Duguid, R, Layzer, H, Panitch
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Oligoclonal IgG bands in chronic inflammatory polyradiculoneuropathies
Journal of Neurology, Neurosurgery & Psychiatry, 2021BackgroundCerebrospinal fluid (CSF) albumincytologic dissociation represents a supportive diagnostic criterion of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).Few studies have investigated possible systemic or intrathecal humoral immune response activation in CIDP.Aim of our study was to investigate whether the search of oligoclonal
Ruiz, Marta +10 more
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Neurology, 1984
Oligoclonal bands ( OCBs ) were examined in CSF from 23 normal controls, 8 cases of inflammatory neurologic diseases, 24 cases of noninflammatory neurologic diseases, 27 sporadic cases of MS, and the 29 MS twin pairs, by isoelectric focusing followed by silver staining or western transblotting and immunoperoxidase staining.
X H, Xu, D E, McFarlin
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Oligoclonal bands ( OCBs ) were examined in CSF from 23 normal controls, 8 cases of inflammatory neurologic diseases, 24 cases of noninflammatory neurologic diseases, 27 sporadic cases of MS, and the 29 MS twin pairs, by isoelectric focusing followed by silver staining or western transblotting and immunoperoxidase staining.
X H, Xu, D E, McFarlin
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Multiple Sclerosis Journal, 2010
a relevant discussion on the use of tears in the diagnosis of ...
LOLLI, FRANCESCO, Franciotta, Diego
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a relevant discussion on the use of tears in the diagnosis of ...
LOLLI, FRANCESCO, Franciotta, Diego
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Oligoclonal restriction of antiviral immunoreaction in oligoclonal band-negative MS patients
Acta Neurologica Scandinavica, 2014Presence of oligoclonal bands (OCB) in cerebrospinal fluid (CSF) is a diagnostic hallmark of multiple sclerosis (MS). However, up to 10% of patients were OCB negative in routine laboratory tests. The aim of this study was to determine whether there is at least an oligoclonal restriction of intrathecal antibody synthesis against measles, rubella and/or ...
Stich, Oliver +3 more
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Practical Neurology
Oligoclonal bands (OCBs) represent the presence of intrathecal immunoglobulin G (IgG) as detected by isoelectric focusing and immunofixation. Cerebrospinal fluid (CSF) analysed alongside a paired serum sample gives five different immunofixation patterns. These are: type 1—the normal physiological state with no intrathecal IgG synthesis; type 2—evidence
Mark D Willis +2 more
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Oligoclonal bands (OCBs) represent the presence of intrathecal immunoglobulin G (IgG) as detected by isoelectric focusing and immunofixation. Cerebrospinal fluid (CSF) analysed alongside a paired serum sample gives five different immunofixation patterns. These are: type 1—the normal physiological state with no intrathecal IgG synthesis; type 2—evidence
Mark D Willis +2 more
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Differential oligoclonal band patterns on polyvinyldifluoride membranes
Journal of Immunological Methods, 1989We report a novel observation which has been reproducibly noted whilst studying immunoglobulin G binding to antigen immobilized on polyvinyldifluoride membranes. In some samples we have observed a difference between the pattern of oligoclonal bands on the front surface when compared to the reverse side of the membrane.
R W, Luxton, E J, Thompson
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