Polyspecific, antiviral immune response distinguishes multiple sclerosis and neuromyelitis optica [PDF]
, 1887 Background: A polyspecific, intrathecal humoral immune response against neurotropic viruses such as measles, rubella and varicella zoster virus (MRZ reaction, MRZR) is present in 80--100% of patients with multiple sclerosis (MS), but has not to date been
Bergamaschi, R. +12 more
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Haematologica, 2013 The emergence of an oligoclonal humoral response, resulting in the appearance of a different serum M-protein to that observed at diagnosis is a well-recognized event after autologous stem cell transplantation in multiple myeloma in complete response, and
Natalia Tovar +9 more
doaj +1 more source
Haematologica, 2011 The emergence of oligoclonal bands is associated with a favorable outcome after autologous stem cell transplantation in multiple myeloma. The aim of this study was to determine the prevalence of immunoglobulin oligoclonality in 33 patients with multiple ...
Carlos Fernández de Larrea +8 more
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Leptomeningitis in a person with radiologically isolated syndrome and latent tuberculosis. A case report with implications for clinical research [PDF]
, 2018 A 39-year-old man, followed with serial MRI of CNS for a radiologically isolate syndrome (RIS, a recently described condition considered a subclinical form of MS), was hospitalized for the occurrence of a leptomeningitis. Routine blood tests and contrast
Bozzao, Alessandro +8 more
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Impact of the McDonald Criteria 2017 on Early Diagnosis of Relapsing-Remitting Multiple Sclerosis
Frontiers in Neurology, 2019 Multiple sclerosis is a chronic immune mediated demyelinating disease leading to neurological disabilities that need to be diagnosed and treated early. Guidelines on multiple sclerosis diagnosis and monitoring experienced comprehensive changes over the ...
Philipp Schwenkenbecher +7 more
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Cerebrospinal fluid CXCL13 in clinically isolated syndrome patients: Association with oligoclonal IgM bands and prediction of Multiple Sclerosis diagnosis [PDF]
, 2015 Cerebrospinal fluid (CSF) CXCL13 was shown to correlate with markers of intrathecal inflammation and CSF oligoclonal IgM bands (IgMOB) have been associated with a more severe Multiple Sclerosis (MS) course.We correlated CSF CXCL13 levels with clinical ...
BEDIN, Roberta +9 more
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Cerebrospinal fluid anti-Epstein-Barr virus specific oligoclonal IgM and IgG bands in patients with clinically isolated and Guillain-Barré syndrome [PDF]
, 2016 Epstein-Barr virus (EBV) has been implicated in multiple sclerosis (MS) pathogenesis. We aimed to assess the frequency of EBV-specific IgG and IgM oligoclonal bands (OCB) in cerebrospinal fluid (CSF) of 50 patients with clinically isolated syndrome (CIS)
BEDIN, Roberta +7 more
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Cerebrospinal fluid humoral immunity in the differential diagnosis of multiple sclerosis. [PDF]
PLoS ONE, 2017 The diagnostic accuracy of cerebrospinal fluid oligoclonal bands (CSF-OCB) detected by isoelectric focusing (IEF) in patients with multiple sclerosis (MS) was evaluated in our study.Three hundred and twenty-one patients with MS and other central nervous ...
Evanthia Bernitsas +7 more
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Prognostic significance of intrathecal oligoclonal immunoglobulin G in multiple sclerosis [PDF]
Scripta Medica, 2020 Introduction/Aim: Detection of intrathecal oligoclonal bands of immunoglobulin G (OB IgG), in addition to diagnostic, has a predictive significance in multiple sclerosis (MS).
Grgić Sanja +6 more
doaj
Multiple sclerosis in Brazil: analysis of cerebrospinal fluid by standard methods [PDF]
Arquivos de Neuro-Psiquiatria, 1999 The demonstration of intrathecal IgG synthesis has been used as an important laboratory parameter to support the diagnosis of multiple sclerosis(MS). The Committee for European Concerted Action for Multiple Sclerosis has recommended a protocol for the ...
MARZIA PUCCIONI-SOHLER +4 more
doaj +1 more source