Estudo de bandas oligoclonais restritas ao líquido cefalorraquidiano em pacientes com esclerose múltipla na cidade de São Paulo [PDF]
The frequency of oligoclonal bands (OCB) restricted to the cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) varies widely in different populations.
ADONI, Tarso +9 more
core +2 more sources
Cerebrospinal fluid humoral immunity in the differential diagnosis of multiple sclerosis. [PDF]
The diagnostic accuracy of cerebrospinal fluid oligoclonal bands (CSF-OCB) detected by isoelectric focusing (IEF) in patients with multiple sclerosis (MS) was evaluated in our study.Three hundred and twenty-one patients with MS and other central nervous ...
Evanthia Bernitsas +7 more
doaj +1 more source
Cerebrospinal fluid anti-myelin antibodies are related to magnetic resonance measures of disease activity in multiple sclerosis [PDF]
0.001), together constituting 85% of all positive CSF samples. In contrast, elevated anti-myelin IgG antibody reactivity was present in a minority of IND patients (21%), marginally present in controls (5%) and absent in OND patients (0%). Most strikingly,
Breij, E.C.W. +8 more
core +1 more source
Prognostic significance of intrathecal oligoclonal immunoglobulin G in multiple sclerosis [PDF]
Introduction/Aim: Detection of intrathecal oligoclonal bands of immunoglobulin G (OB IgG), in addition to diagnostic, has a predictive significance in multiple sclerosis (MS).
Grgić Sanja +6 more
doaj
Multiple sclerosis in Brazil: analysis of cerebrospinal fluid by standard methods [PDF]
The demonstration of intrathecal IgG synthesis has been used as an important laboratory parameter to support the diagnosis of multiple sclerosis(MS). The Committee for European Concerted Action for Multiple Sclerosis has recommended a protocol for the ...
MARZIA PUCCIONI-SOHLER +4 more
doaj +1 more source
Intrathecal B-cell activation in LGI1 antibody encephalitis. [PDF]
ObjectiveTo study intrathecal B-cell activity in leucine-rich, glioma-inactivated 1 (LGI1) antibody encephalitis. In patients with LGI1 antibodies, the lack of CSF lymphocytosis or oligoclonal bands and serum-predominant LGI1 antibodies suggests a ...
Dandekar, Ravi +13 more
core
Cerebrospinal fluid anti-Epstein-Barr virus specific oligoclonal IgM and IgG bands in patients with clinically isolated and Guillain-Barré syndrome [PDF]
Epstein-Barr virus (EBV) has been implicated in multiple sclerosis (MS) pathogenesis. We aimed to assess the frequency of EBV-specific IgG and IgM oligoclonal bands (OCB) in cerebrospinal fluid (CSF) of 50 patients with clinically isolated syndrome (CIS)
BEDIN, Roberta +7 more
core +1 more source
Background Steps towards the development of diagnostic criteria are needed for children with the radiologically isolated syndrome to identify children at risk of clinical demyelination.
Naila Makhani +31 more
doaj +1 more source
A 50 year old with a rapid neuropsychiatric deterioration and choreaform movements [PDF]
A 50-year-old man presented acutely to the hospital with behavioural disturbance, choreiform movements and profound nihilistic delusions. He reported recent drug and alcohol abuse, and also apparent involvement in several recent criminal activities, for ...
Campbell, Stewart +3 more
core +1 more source
Reiber’s Diagram for Kappa Free Light Chains: The New Standard for Assessing Intrathecal Synthesis?
Oligoclonal bands are the gold standard for determination of an intrathecal immunoglobulin G synthesis and were recently included in the McDonald criteria of 2017 to diagnose relapsing multiple sclerosis (MS) as a substitute for dissemination in time ...
Philipp Schwenkenbecher +7 more
doaj +1 more source

