Results 21 to 30 of about 18,346 (233)

Assessing the presence of oligoclonal IgM bands as a prognostic biomarker of cognitive decline in the early stages of multiple sclerosis

open access: yesBrain and Behavior, 2021
Background An association has been found between the presence of lipid‐specific oligoclonal IgM bands (LS‐OCMB) in cerebrospinal fluid and a more severe clinical multiple sclerosis course.
Clàudia Coll‐Martinez   +11 more
doaj   +1 more source

Oligoclonal free light chains in cerebrospinal fluid as markers of intrathecal inflammation. Comparison with oligoclonal IgG

open access: yesBiomedical Papers, 2015
Aims: To compare the sensitivity and specificity of CSF-restricted oligoclonal IgG and free light chains as markers of multiple sclerosis and other inflammatory neurological diseases.
David Zeman   +6 more
doaj   +1 more source

Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine [PDF]

open access: yes, 2016
In the field of predictive, preventive and personalised medicine, researchers are keen to identify novel and reliable ways to predict and diagnose disease, as well as to monitor patient response to therapeutic agents.
A Acera   +183 more
core   +2 more sources

A CPH-Like Picture in Two Patients with an Orbitocavernous Sinus Syndrome [PDF]

open access: yes, 1997
Two patients with retroorbital pain syndromes with or without paresis of cranial nerves developed weeks after ipsilateral headache resembling chronic paroxysmal hemicrania (CPH) but without autonomic features.
A Straube   +5 more
core   +1 more source

Natural history and prognostic impact of oligoclonal humoral response in patients with multiple myeloma after autologous stem cell transplantation: long-term results from a single institution

open access: yesHaematologica, 2013
The emergence of an oligoclonal humoral response, resulting in the appearance of a different serum M-protein to that observed at diagnosis is a well-recognized event after autologous stem cell transplantation in multiple myeloma in complete response, and
Natalia Tovar   +9 more
doaj   +1 more source

Leptomeningitis in a person with radiologically isolated syndrome and latent tuberculosis. A case report with implications for clinical research [PDF]

open access: yes, 2018
A 39-year-old man, followed with serial MRI of CNS for a radiologically isolate syndrome (RIS, a recently described condition considered a subclinical form of MS), was hospitalized for the occurrence of a leptomeningitis. Routine blood tests and contrast
Bozzao, Alessandro   +8 more
core   +1 more source

Emergence of oligoclonal bands in patients with multiple myeloma in complete remission after induction chemotherapy: association with the use of novel agents

open access: yesHaematologica, 2011
The emergence of oligoclonal bands is associated with a favorable outcome after autologous stem cell transplantation in multiple myeloma. The aim of this study was to determine the prevalence of immunoglobulin oligoclonality in 33 patients with multiple ...
Carlos Fernández de Larrea   +8 more
doaj   +1 more source

Cerebrospinal Fluid Analysis in Multiple Sclerosis Diagnosis: An Update [PDF]

open access: yes, 2019
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS) with brain neurodegeneration. MS patients present heterogeneous clinical manifestations in which both genetic and environmental factors are involved ...
Bruna Lo Sasso   +4 more
core   +1 more source

Multiple Sclerosis and Schizophrenia [PDF]

open access: yes, 2017
The psychiatric and neurological aspects of health may present methodological challenges in the diagnosis and treatment of disease. This is especially true for patients whose symptoms indicate the coexistence of multiple sclerosis (MS) and schizophrenia (
Arneth, Borros M
core   +1 more source

Impact of the McDonald Criteria 2017 on Early Diagnosis of Relapsing-Remitting Multiple Sclerosis

open access: yesFrontiers in Neurology, 2019
Multiple sclerosis is a chronic immune mediated demyelinating disease leading to neurological disabilities that need to be diagnosed and treated early. Guidelines on multiple sclerosis diagnosis and monitoring experienced comprehensive changes over the ...
Philipp Schwenkenbecher   +7 more
doaj   +1 more source

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