Results 71 to 80 of about 18,346 (233)

Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients. [PDF]

PLoS ONE, 2013
to explore the association between genetic markers and Oligoclonal Bands (OCB) in the Cerebro Spinal Fluid (CSF) of Italian Multiple Sclerosis patients.We genotyped 1115 Italian patients for HLA-DRB1*15 and HLA-A*02. In a subset of 925 patients we tested
Maurizio A Leone, Nadia Barizzone, Federica Esposito, Ausiliatrice Lucenti, Hanne F Harbo, An Goris, Ingrid Kockum, Annette Bang Oturai, Elisabeth Gulowsen Celius, Inger L Mero, Bénédicte Dubois, Tomas Olsson, Helle Bach Søndergaard, Daniele Cusi, Sara Lupoli, Bettina Kulle Andreassen, International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium 2, Kjell-Morten Myhr, Franca R Guerini, PROGEMUS Group, PROGRESSO Group, Giancarlo Comi, Filippo Martinelli-Boneschi, Sandra D'Alfonso   +24 more
doaj   +1 more source

Amyotrophic Lateral Sclerosis and Multiple Sclerosis Overlap: A Case Report [PDF]

, 2012
The concurrence of amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) is extremely rare. We reported the case of a 33-year-old woman with a past history of paresthesias at the right hand, who developed progressive quadriparesis with muscular
Anna Sagnelli, Cinzia Femiano, Francesca Trojsi, Francesco Izzo, Gioacchino Tedeschi, Giovanni Cirillo, Giovanni Piccirillo, Maria Rosaria Monsurrò   +7 more
core   +1 more source

Oligoclonal M bands unveil occult inflammation in multiple sclerosis

Multiple Sclerosis and Related Disorders, 2022
Recent works demonstrate that patients with multiple sclerosis (pwMS) and oligoclonal M bands (OCMB) in cerebrospinal fluid (CSF) are at higher risk of conversion to secondary progressive course, suggesting a distinct pathophysiology pathway in these patients.To analyze the relationship of serum neurofilament light chain (s-NFL) in absence of ...
Bonaventura Casanova, Jessica Castillo, Carlos Quintanilla-Bordás, María T. Sanz, Jose I Fernández-Velasco, Carmen Alcalá, Sara Carratalá, Raquel Gasque, Almudena Rubio, Laura Cubas, Luisa María Villar, Francisco Pérez-Miralles   +11 more
openaire   +3 more sources

Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti‐LGI1 Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Anti–leucine‐rich glioma‐inactivated 1 encephalitis (LGI1‐E) can cause persistent cognitive deficits, but the mechanisms remain unclear. A 40‐year‐old woman with LGI1‐E presented with subacute cognitive deficits and showed mild left medial temporal lobe (MTL) swelling and fluid‐attenuated inversion recovery (FLAIR) hyperintensity on initial ...
Yusuke Akitomi, Kenichiro Taira, Masanori Kurihara, Kenji Ishibashi, Kenji Ishii, Fumio Suzuki, Aya Midori Tokumaru, Makoto Hara, Atsushi Iwata   +8 more
wiley   +1 more source

Associations of HLA DRB1 alleles with IgG oligoclonal bands and their influence on multiple sclerosis course and disability status

Medicina, 2016
Background and aim: Oligoclonal bands (OCB) may be associated with the genes of HLA complex, which allows to consider the possible interaction of genetic and immunological factors and its importance in the development and progression of multiple ...
Renata Balnytė, Daiva Rastenytė, Antanas Vaitkus, Erika Skrodenienė, Astra Vitkauskienė, Ingrida Ulozienė   +5 more
doaj   +1 more source

Clinically isolated syndrome: Diagnosis and risk of developing clinically definite multiple sclerosis

Neurología (English Edition), 2023
Introduction: In most cases, multiple sclerosis (MS) initially presents as clinically isolated syndrome (CIS). Differentiating CIS from other acute or subacute neurological diseases and estimating the risk of progression to clinically definite MS is ...
J. López-Gómez, B. Sacristán Enciso, M.A. Caro Miró, M.R. Querol Pascual   +3 more
doaj   +1 more source

Neurosyphilis presenting with papillitis [PDF]

, 2017
Syphilis is one of the oldest described infectious diseases in the world and is caused by the spirochete bacterium Treponema pallidum[1]. Although now a rare disease, incidence is increasing with the number of diagnoses of the disease rising in England ...
Cooper, Sarah, Corry, Shona, Perry, Martin Edward   +2 more
core   +4 more sources

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Age-related increase of kynurenic acid in human cerebrospinal fluid-IgG and beta(2)-microglobulin changes [PDF]

, 2005
Kynurenic acid (KYNA) is an endogenous metabolite in the kynurenine pathway of tryptophan degradation and is an antagonist at the glycine site of the N-methyl-D-aspartate as well as at the alpha 7 nicotinic cholinergic receptors. In the brain tissue KYNA
Baran, H, Ferraz-Leite, H, Kainz, A, Kalina, P, Kepplinger, B, Newcombe, J   +5 more
core