Results 191 to 200 of about 190,260 (351)

Tunable Thermotropic Liquid Crystals Using Amphiphilic Sequence-Defined Macromolecules. [PDF]

JACS Au
De Franceschi I, Beyer VP, Huband S, Badi N, Perrier S, Du Prez FE.   +5 more
europepmc   +1 more source

Architecture‐Engineered Semi‐Crystalline Microporous Polymer Membranes for Precise Molecular Separation

Advanced Science, EarlyView.
Guided by a Random Forest model, a π–π‐driven ordered stacking strategy deploys functionally distinct substructures to restrict chain segment motion and increase free volume, while preserving the intermolecular interactions that maintain structural integrity.
Zi‐Meng Xu, Hao Zhuo, Song‐Hui Zhi, Xiao‐Feng Zhong, Pan‐Pan Zhang, Si‐Yuan Yang, Wen‐Yong Yang, Guang‐Yong Shen, Ya‐Zhao Li, Yi Li, Ming Xue   +10 more
wiley   +1 more source

Shrinking of Extracellular Space During Metabolic Stress Accelerates Amyloid-β Aggregation. [PDF]

Biomolecules
De Oliveira LF, Karunarathne K, Zona D, Muschol M, Ullah G.   +4 more
europepmc   +1 more source

Synthesis and Properties of New Glassy Molecular and Oligomer Azocompounds Suitable for Holographic Recordings

Synthesis and Properties of New Glassy Molecular and Oligomer Azocompounds Suitable for Holographic ...
Traskovskis, Kaspars, Kokars, Valdis, Ozols, Andris, Augustovs, Pēteris   +3 more
core  

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Multimerization of a rationally designed nanobody for enhanced avidity toward Aβ42 oligomers. [PDF]

Protein Sci
Nowinska M, Suh E, Mogilevsky C, Vendruscolo M.   +3 more
europepmc   +1 more source

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

Advanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu, Yufan Xie, Lanxin Wang, Luyan Ma, Xiaofei Ge, Jiawei Wang   +5 more
wiley   +1 more source

Assembling peptides for treating Alzheimer's disease: a supramolecular perspective. [PDF]

RSC Adv
Fang X, Zhang Z, Hu X, Zhang M, Yang H, He J, Shi Y, Li G, Jia Y.   +8 more
europepmc   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

An Energy-Gradient Strategy for Triplet-Pair Separation in Singlet-Fission Oligomers. [PDF]

J Am Chem Soc
Sebastian E, Montanaro S, Millington O, Sharma A, Leventis A, Osmólska J, Congrave DG, Rao A, Bronstein H.   +8 more
europepmc   +1 more source