Results 221 to 230 of about 190,260 (351)

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Corrigendum to "Trem2 mediated Syk-dependent ROS amplification is essential for osteoclastogenesis in periodontitis microenvironment" [Redox Biol. 40 (2021) 101849]. [PDF]

Redox Biol
Weng Y, Wang H, Li L, Feng Y, Xu S, Wang Z.   +5 more
europepmc   +1 more source

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.

Brain : a journal of neurology, 2014
E. Rockenstein, S. Nuber, C. Overk, K. Ubhi, M. Mante, C. Patrick, A. Adame, M. Trejo-Morales, J. Gerez, P. Picotti, P. Jensen, Silvia Campioni, R. Riek, J. Winkler, F. Gage, B. Winner, E. Masliah   +16 more
semanticscholar   +1 more source

Side‐Chain Asymmetry in Quinoxaline Copolymer Donors Enables Optimal Morphology and Improved Charge Dynamics for High‐Efficiency Organic Solar Cells

Advanced Science, EarlyView.
Side‐chain asymmetry in quinoxaline copolymer donors modulates donor–acceptor miscibility and blend morphology in all‐polymer solar cells. The asymmetric donor PBAQ6 enables more balanced charge transport, reduced recombination, and improved charge dynamics with PYF‐T‐o, delivering PCEs of 18.35% in binary devices and 19.52% in ternary devices ...
Can Zhu, Jinyuan Zhang, Ke Hu, Shirong Lu, Jianqi Zhang, Shucheng Qin, Hong Zhang, Yule Cheng, Wenbin Lai, Beibei Qiu, Jing Guo, Lei Meng, Gang Li, Yongfang Li   +13 more
wiley   +1 more source

Transcobalamin receptor CD320, responsible for vitamin B₁₂ cellular uptake, is present on the cell surface as a homo-oligomer. [PDF]

J Biol Chem
Guo W, Qiu R, Zhao X, Zhou T, Liu M, Dong N, Wu Q.   +6 more
europepmc   +1 more source

Mechanophore‐Based Multichannel Colorimetric Force Sensors: Ultrasound‐Driven Stress and Strain Quantification

Advanced Science, EarlyView.
ABSTRACT Mechanophores with mechanochromic properties have attracted significant attention as force‐responsive materials for structural sensing. However, their applications remain mainly limited to qualitative force visualization, as direct and quantitative extraction of mechanical parameters such as stress and strain from mechanochromic responses has ...
Seungo Baek, Jeong Hoon Rhee, Skylar K. Osler, Minsoo P. Kim, Shyuan Cheng, Leonardo P. Chamorro, Hyunhyub Ko, Maxwell J. Robb, Gun Kim   +8 more
wiley   +1 more source

Isolation and characterization of plant plasma membrane P-type H⁺-ATPase dimers. [PDF]

Sci Rep
Malysenko E, Günther Pomorski T, Justesen BH.   +2 more
europepmc   +1 more source

Solution Structure of Apoptotic BAX Oligomer: Oligomerization Likely Precedes Membrane Insertion.

Structure, 2015
Tai-Ching Sung, Ching-Yu Li, Yei-Chen Lai, Chien-Lun Hung, O. Shih, Yi-Qi Yeh, U. Jeng, Yun-Wei Chiang   +7 more
semanticscholar   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

Generation of Interstrand DNA Cross-Links under Conditions of Acid Stress. [PDF]

Chem Res Toxicol
Mumu MF, Heidari M, Mahbub MS, Gates KS.
europepmc   +1 more source