Results 171 to 180 of about 133,297 (213)
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Oligomerization of oncoprotein p53
Journal of Virology, 1988Cellular phosphoprotein p53, which seems to be a multifunctional protein, may be assigned to different structural subclasses. Recently established immortalized or transformed cell lines that overexpress p53 allowed us to perform a detailed analysis of the quaternary structure of p53.
S, Kraiss +3 more
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Dimeric and Oligomeric Steroids
Chemical Reviews, 1997The steroid nucleus is one of the largest rigid units readily available with multiple chiral centers and the biological importance of this structural entity is well documented.1 While dimeric steroids were first observed as synthetic byproducts2,3 and then discovered in nature,4 up to very recently, dimeric steroid systems were considered more of a ...
Yuexian, Li, Jerry Ray, Dias
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Current Alzheimer Research, 2008
The PrP propensity to adopt different structures is tightly linked to transmissible spongiform encephalopathies (TSE) which include Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scjeinker (GSS) and Kuru syndrome. In most cases, TSE is associated with the accumulation in the brain of an abnormally folded protease-resistant protein, PrP Sc or ...
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The PrP propensity to adopt different structures is tightly linked to transmissible spongiform encephalopathies (TSE) which include Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scjeinker (GSS) and Kuru syndrome. In most cases, TSE is associated with the accumulation in the brain of an abnormally folded protease-resistant protein, PrP Sc or ...
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Protein oligomerization: How and why
Bioorganic and Medicinal Chemistry, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
Barbara Imperiali
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Hydrodebromination and Oligomerization of Dibromomethane
ACS Catalysis, 2012CH 3Br, like CH 3OH in the Methanol-To-Gasoline process, can be readily directly converted to petrochemicals and liquid fuels. CH 3Br can be obtained in high yields by the direct bromination of methane using relatively low reaction temperatures and pressure, but with the formation of dibromomethane (DBM) as a primary side product.
Ding, Kunlun +7 more
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Oligomerization of Retrovirus Integrases
2018Integration of the reverse-transcribed viral cDNA into the host's genome is a critical step in the lifecycle of all retroviruses. Retrovirus integration is carried out by integrase (IN), a virus-encoded enzyme that forms an oligomeric 'intasome' complex with both ends of the linear viral DNA to catalyze their concerted insertions into the backbones of ...
Duane P, Grandgenett, Hideki, Aihara
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Oligomerization of opioid receptors
Methods, 2002Opioid receptors belong to the family of G-protein-coupled receptors characterized by their seven transmembrane domains. The activation of these receptors by agonists such as morphine and endogenous opioid peptides leads to the activation of inhibitory G-proteins followed by a decrease in the levels of intracellular cAMP.
Ivone, Gomes +3 more
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Oligomerization of Monoamine Transporters
Transporters of the monoamine transporter (MAT) family regulate the uptake of important neurotransmitters like dopamine, serotonin, and norepinephrine. The MAT family functions using the electrochemical gradient of ions across the membrane and comprises three transporters, dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine ...Arnav, Paul, Diwakar, Shukla
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Mechanism of Oligomerization Reactions of Silica
The Journal of Physical Chemistry B, 2006The mechanism of the oligomerization reaction of silica, the initial step of silica formation, has been studied by quantum chemical techniques. The solvent effect is included by using the COSMO model. The formation of various oligomers (from dimer to tetramer) was investigated.
Trinh, T.T. +2 more
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2012
This chapter provides a foundation for further research into the relationship between dynamic oligomeric properties and functional diversity. The structural basis that underlies the conformational sub-states of the GAPDH oligomer is discussed. The issue of protein stability is given a thorough analysis, since it is well-established that the primary ...
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This chapter provides a foundation for further research into the relationship between dynamic oligomeric properties and functional diversity. The structural basis that underlies the conformational sub-states of the GAPDH oligomer is discussed. The issue of protein stability is given a thorough analysis, since it is well-established that the primary ...
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