Results 181 to 190 of about 201,093 (287)

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

Mosaic activation of the zebrafish hsp70l heat shock promoter: Implications for interpreting transgenes

Developmental Dynamics, EarlyView.
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley   +1 more source

Ultra‐Fast and Economical Pre‐Breakdown Electrochemical Synthesis of Intrinsically Conductive Polymer Suspension for Production of Safe Lithium‐Ion Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This paper presents a breakthrough pre‐breakdown electrochemical method for synthesizing polyNiMeOSalen suspensions, achieving an 83% yield and nanoscale dispersion ($1500/kg) and environmental impact (1.42 kg CO2eq/kg). We report a novel pre‐breakdown electrochemical synthesis method for producing polyNiMeOSalen suspensions with exceptional ...
Evgenii Beletskii, Valentin Romanovski, Mikhail Pinchuk, Vadim Snetov, Alexey Volkov, Peixia Yang, Yurii K. Gun'ko   +6 more
wiley   +1 more source

LPS-induced structural reorganization and polymerization drive noncanonical inflammasome activation. [PDF]

Sci Adv
Wang C, Lacey P, Tian T, Teran E, Liaqat M, Shivcharan S, Shumba P, He J, Rathinam VA, Wysocki VH, Ruan J.   +10 more
europepmc   +1 more source

Effect of Hydrotreating Severity on Jet Fuel Thermal Oxidation Stability of Olefinic Synthetic Kerosene

Energy Science &Engineering, EarlyView.
The extent of hydrotreating that is required for olefinic kerosene to pass the jet fuel thermal oxidative stability test was investigated. Fouling species are destroyed after mild hydrotreating, and no further benefit is derived from more severe hydrotreating.
Cibele Melo Halmenschlager, Laine Badaro Pereira, Arno de Klerk   +2 more
wiley   +1 more source

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

Gut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei, Xin‐Wei Sun, Hao‐Jie Huang, Yu‐Zhi Zhao, Shuang‐Jiang Liu, Chang Liu   +5 more
wiley   +1 more source

Oligomer-dependent and oligomer-independent pathogenesis of muscular dystrophy-associated mutations within the penta-EF-hand domain of calpain-3. [PDF]

J Biol Chem
Hisatsune C, Shinkai-Ouchi F, Hata S, Ono Y.   +3 more
europepmc   +1 more source

Oligomerization enables the selective targeting of an intrinsically disordered region by a small molecule. [PDF]

Sci Adv
Bielskutė-García S, Mateos B, Awawdy M, Garcia-Cabau C, Niskanen H, Sánchez-Zarzalejo C, Bracaglia L, Pierattelli R, Felli IC, Frigolé-Vivas M, García J, Riera A, Hnisz D, Salvatella X.   +13 more
europepmc   +1 more source

The Berberine Derivative BBR684 Inhibits VDAC Oligomerization to Suppress Ferroptosis in Acute Kidney Injury. [PDF]

Curr Ther Res Clin Exp
Jiang Z, Zhang W, Zhu J, Wang C, Chen G, Guo Y.   +5 more
europepmc   +1 more source

Signaling pathways regulating VDAC1 overexpression associated with apoptosis, pyroptosis, and ferroptosis. [PDF]

Cell Commun Signal
Karunanithi Nivedita A, Santhanam M, Babu V, Shteinfer-Kuzmine A, Garcia Venzor A, Toiber D, Shoshan-Barmatz V.   +6 more
europepmc   +1 more source