Results 191 to 200 of about 201,093 (287)

Mapping Alkyne Chemical Space—Classifying the Reactivity of Alkynes in Semihydrogenation and beyond Using a Data Science Framework

Helvetica Chimica Acta, EarlyView.
A data science framework integrating DFT featurization and hierarchical clustering was used to map the chemical space of over 2700 alkynes into six subsets before using experimental data for Ni3Zn‐catalyzed semihydrogenation and applying a logistic regression model to categorize substrates by reactivity.
Jordan De Jesus Silva, Scott R. Docherty, Jasper Clarysse, Maksym Yarema, Vanessa Wood, Christophe Copéret   +5 more
wiley   +1 more source

Cannabidiol Regulates CD47 Expression and Apoptosis in Jurkat Leukemic Cells Dependent upon VDAC-1 Oligomerization. [PDF]

Pharmaceuticals (Basel)
Wang L, Samarani S, Fadzeyeva E, Vigano M, As'sadiq A, Vulesevic B, Ahmad A, Costiniuk CT.   +7 more
europepmc   +1 more source

Conjugation‐mediated and polarity‐switchable interfacial layers for fast cycling of lithium‐metal batteries

InfoMat, EarlyView.
Thiophene‐embedded solid electrolyte interphase exhibits switchable polarity for uniform Li plating, and the electron‐rich cathode electrolyte interphase stabilizes high‐valence Ni ions in the cathode. These molecularly engineered interfacial layers enable fast cycling of lithium‐metal batteries for practical applications.
Jeong‐A. Lee, Haneul Kang, Yoonhan Cho, Seong Hyeon Kweon, Seonghyun Kim, Syed Azkar UI Hasan, Minju Song, Saehun Kim, Eunji Kwon, Samuel Seo, Kyoung Han Ryu, Rama K. Vasudevan, Sang Kyu Kwak, Seungbum Hong, Nam‐Soon Choi   +14 more
wiley   +1 more source

The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities. [PDF]

MedComm (2020)
Zou C, Jiang S, Li H, Zhao K, Cao D, Yang G.   +5 more
europepmc   +1 more source

A Shock‐Tube Study of the HCl + M →$\to $ H + Cl + M (M = Ar) Rate Constant Using HCl Laser Absorption Near 3.3 µm

International Journal of Chemical Kinetics, EarlyView.
ABSTRACT Hydrogen chlorine (HCl) is an important combustion intermediate during plastic (municipal waste) and composite propellant (aerospace) combustion, but the understanding of its high‐temperature chemistry is still evolving. In this study, the pyrolysis of 0.5% HCl in Ar was investigated behind reflected shock waves in a shock tube at temperatures
Claire M. Grégoire, Olivier Mathieu, Eric L. Petersen   +2 more
wiley   +1 more source

Involvement of the miR‐128‐3p/KDM3A/NLRP3 Axis in High Glucose‐Induced Inflammatory Injury in Retinal Endothelial Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explores the regulatory mechanism of the miR‐128‐3p in diabetic retinopathy (DR)‐associated inflammatory injury. A cellular model of DR was established by inducing immortalized human retinal endothelial cells (IM‐HRECs) with high‐glucose (HG).
Wei‐Ming Wen, Jian‐Bo Feng, Yin‐Sheng Cai, Nan Lin, Fei Lv, Zhu‐Sheng Guo   +5 more
wiley   +1 more source

The value of NLRP, PCT, and HBP for sepsis-associated acute kidney injury and the effect of anti-inflammatory drugs. [PDF]

Medicine (Baltimore)
Fang Z, Cui S, Liu X, Shi M, Zheng W, Xue J, Chen L.   +6 more
europepmc   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen, Yong‐Hong Yu, Yan‐Hua Du, Lin Xu, Xiang‐Ping Meng   +4 more
wiley   +1 more source

Molecular Mechanism of the IRF1/NFE2L1‐DT/ALKBH5/Cx43 Axis in Radiation‐Induced Injury in Vascular Endothelial Cells Through Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li, Jia‐Wen Yang, Yong‐Rui Jia, Jie Zhang, Qiao Gou   +4 more
wiley   +1 more source

High-Speed Atomic Force Microscopy Reveals Disordered Region-Mediated Structural Plasticity of Anaplastic Lymphoma Kinase Fusion Proteins Induced by Inhibitors. [PDF]

ACS Nano
Han X, Kodera N, Yilmaz N, Sakai K, Arai S, Li B, Imamura R, Voon DC, Fukuda K, Nanjo S, Flechsig H, Mano H, Matsumoto K, Yano S.   +13 more
europepmc   +1 more source