Results 221 to 230 of about 202,274 (300)

Huntingtin as an Actin Organizer: Structural and Functional Insights

Cytoskeleton, EarlyView.
M. Capizzi, S. Humbert
wiley   +1 more source

When Infection Meets Inflammation: <i>Listeria monocytogenes</i> and Host Signaling Pathways. [PDF]

Biology (Basel)
Jia Y, Yang K, Guo R, Ding K, Wang S, Chen S.   +5 more
europepmc   +1 more source

Cannabidiol Regulates CD47 Expression and Apoptosis in Jurkat Leukemic Cells Dependent upon VDAC-1 Oligomerization. [PDF]

Pharmaceuticals (Basel)
Wang L, Samarani S, Fadzeyeva E, Vigano M, As'sadiq A, Vulesevic B, Ahmad A, Costiniuk CT.   +7 more
europepmc   +1 more source

Telomeric repeat-containing RNA G-quadruplexes trigger ZBP1-mediated cell death. [PDF]

Nat Commun
Qin G, Zhao C, Gao C, Hu W, Zhang N, Ren J, Qu X.   +6 more
europepmc   +1 more source

Second‐trimester multimetabolite panel for early preeclampsia rule‐out

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins, Julyane N. S. Kaihara, Diego Fortes Salgueiro, Viviane Cunha Cardoso, Silvana Maria Quintana, Ricardo Carvalho Cavalli, Valerio Garrone Barauna, Valeria Cristina Sandrim   +7 more
wiley   +1 more source

Caspase-8 homo-oligomerization induces apoptosis and suppresses necroptosis to regulate tissue homeostasis

Pasparakis M, Stair N, Seiler J, Mannion J, de Vasconcelos N, Meier P, Craxton A, MacFarlane M, Wachsmuth L.   +8 more
europepmc   +1 more source

The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities. [PDF]

MedComm (2020)
Zou C, Jiang S, Li H, Zhao K, Cao D, Yang G.   +5 more
europepmc   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

The value of NLRP, PCT, and HBP for sepsis-associated acute kidney injury and the effect of anti-inflammatory drugs. [PDF]

Medicine (Baltimore)
Fang Z, Cui S, Liu X, Shi M, Zheng W, Xue J, Chen L.   +6 more
europepmc   +1 more source