Results 31 to 40 of about 14,081 (169)

Oligometastatic Hormone-Sensitive Prostate Cancer. Why Radiotherapy?

, 2022
20.500.12530/87854Androgen deprivation therapy (ADT) has been considered for years the standard initial treatment for patients with metastatic prostate cancer (mPC).
Fernando López-Campos, Marian Gómez Aparicio, Couñago, Felipe, Manuel Galdeano Rubio, Arcos, Marta Barrado Los, López-Campos, Fernando, Ignacio Visus Fernández de Manzanos, Siva, Shankar, Vérane Achard, de Manzanos, Ignacio Visus Fernández, Valcarcel, Marta López, Rubio, Manuel Galdeano, Juan Zafra Martin, Shankar Siva, Marta López Valcarcel, Felipe Couñago, Martin, Juan Zafra, Duque-Santana, Víctor, Achard, Vérane, Marta Barrado Los Arcos, Amar U. Kishan, Kishan, Amar U, Aparicio, Marian Gómez, Víctor Duque-Santana   +23 more
core   +1 more source

A Case of Adjuvant Brigatinib in a Patient with ALK-rearranged R0 Resected Oligometastatic Lung Cancer [PDF]

Anaplastic lymphoma kinase (ALK) rearrangement is detected at a low rate in non-small cell lung cancer (NSCLC). Patients with ALK rearrangements have poor responses to conventional cytotoxic chemotherapy.
Nalan Akyürek, Osman Yüksel, Oktay Ünsal, Ahmet Özet, Abdullah İrfan Taştepe   +4 more
core   +1 more source

MicroRNA expression characterizes oligometastasis(es). [PDF]

PLoS ONE, 2011
Cancer staging and treatment presumes a division into localized or metastatic disease. We proposed an intermediate state defined by ≤ 5 cumulative metastasis(es), termed oligometastases.
Yves A Lussier, H Rosie Xing, Joseph K Salama, Nikolai N Khodarev, Yong Huang, Qingbei Zhang, Sajid A Khan, Xinan Yang, Michael D Hasselle, Thomas E Darga, Renuka Malik, Hanli Fan, Samantha Perakis, Matthew Filippo, Kimberly Corbin, Younghee Lee, Mitchell C Posner, Steven J Chmura, Samuel Hellman, Ralph R Weichselbaum   +19 more
doaj   +1 more source

A phase II randomized trial of metastasis-directed therapy with alpha emitter radium-223 in men with oligometastatic castration-resistant prostate cancer (MEDAL)

BMC Urology, 2023
Background The significance of metastasis-directed therapy for oligometastatic prostate cancer has been widely discussed, and targeted therapy for progressive sites is a feasible option as a multidisciplinary treatment for castration-resistant prostate ...
Soichiro Yoshida, Taro Takahara, Yuki Arita, Masaya Ito, Sara Hayakawa, Tomohiko Oguchi, Yoshinobu Komai, Noboru Numao, Takeshi Yuasa, Masaharu Inoue, Hiroki Ushijima, Shigehiro Kudo, Yasumasa Shimano, Yuki Nakamura, Yusuke Uchida, Sho Uehara, Hajime Tanaka, Hiroshi Yaegashi, Kouji Izumi, Minato Yokoyama, Yoh Matsuoka, Yasuo Yoshioka, Koji Konishi, Katsuyuki Nakanishi, Akira Nagahara, Akihiro Hirakawa, Ryuji Koike, Fumitaka Koga, Kazuo Nishimura, Atsushi Mizokami, Junji Yonese, Yukio Kageyama, Ryoichi Yoshimura, Yasuhisa Fujii   +33 more
doaj   +1 more source

Survival Impact of Aggressive Treatment and PD-L1 Expression in Oligometastatic NSCLC

Current Oncology, 2021
Background: Studies have shown that aggressive treatment of non-small cell lung cancer (NSCLC) with oligometastatic disease improves the overall survival (OS) compared to a palliative approach and some immunotherapy checkpoint inhibitors, such as anti ...
Camille Gauvin, Vimal Krishnan, Imane Kaci, Danh Tran-Thanh, Karine Bédard, Roula Albadine, Charles Leduc, Louis Gaboury, Normand Blais, Mustapha Tehfe, Bertrand Routy, Marie Florescu   +11 more
doaj   +1 more source

Oligometastatic Disease: When Stage IV Breast Cancer Could Be “Cured”

, 2022
Although metastatic breast cancer remains an incurable disease, there are patients with a limited number of metastatic lesions that, in addition to systemic therapy, can be treated with “radical therapy” and sometimes reach the status of no long-term ...
Gion, Maria, Saavedra, Cristina, Cortes, Javier, Javier Cortes, Cristina Saavedra, Jose Perez-Garcia, Maria Gion, Perez-Garcia, Jose   +7 more
core   +1 more source

Survival patterns after perioperative treatment escalation and cystectomy for synchronous oligometastatic bladder cancer (M1a/M1b) – a population-based series

Scandinavian Journal of Urology
Background: The role of cystectomy in synchronous oligometastatic bladder cancer is unclear. Objective: To describe a population-based consecutive cohort with primary oligometastatic bladder cancer (M1a or M1b) treated with curative intent.  Methods:
Fredrik Liedberg, Gediminas Baseckas, Mats Bläckberg, Ragna Fridriksdottir, Axel Gerdtsson, Oskar Hagberg, Sofia Kjellström, Petter Kollberg, Ioannis Patras, Elin Ståhl, Olof Ståhl, Anne Sörenby, Elin Trägårdh, Åsa Warnolf, Johannes Bobjer   +14 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Ablative Techniques for Sarcoma Metastatic Disease: Current Role and Clinical Applications

Medicina, 2023
Sarcomas are heterogenous mesenchymal neoplasms with more than 80 different histologic subtypes. Lung followed by liver and bone are the most common sites of sarcoma metastatic disease.
Evgenia Efthymiou, Georgios Charalampopoulos, Georgios Velonakis, Stauros Grigoriadis, Alexis Kelekis, Nikolaos Kelekis, Dimitrios Filippiadis   +6 more
doaj   +1 more source

Head and Neck Lymph Node Metastases From Cancer of Unknown Primary: Outcomes From p16‐Guided Mucosal Radiotherapy

Head &Neck, EarlyView.
ABSTRACT Background The AJCC 8th edition distinguishes p16‐positive oropharyngeal head and neck carcinoma of unknown primary (HNCUP) due to its superior prognosis. However, standardized radiation volume guidelines are lacking. This study evaluates the safety of p16‐guided mucosal volume reduction.
Philippe Harris, Dhiya‐Eddine Mabrouki, Felix‐Phuc Nguyen‐Tan, Edith Filion, Olivier Ballivy, Brian O'Sullivan, Apostolos Christopoulos, Tareck Ayad, Louis Guertin, Eric Bissada, Paul Tabet, Denis Soulières, Antoine Desilets, Alexandre Pellan Cheng, Robert Doucet, Laurent Létourneau‐Guillon, Houda Bahig   +16 more
wiley   +1 more source