Results 191 to 200 of about 641,320 (378)

Synthesis and fluorescence study of 7-azaindole in DNA oligonucleotides replacing a purine base

, 2002
Ke Wang, Sandra Stringfellow, Shiming Dong, Yugao Jiao, Hongtao Yu   +4 more
openalex   +2 more sources

Luminescence Quenching of Ru-Labeled Oligonucleotides by Targeted Complementary Strands [PDF]

, 2002
David García‐Fresnadillo, Nathalie Boutonnet, Stephan Schumm, Cécile Moucheron, Andrée Kirsch‐De Mesmaeker, Éric Defrancq, Jean‐François Constant, J. Lhomme   +7 more
openalex   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Four hydrogen-bonding motifs in oligonucleotides

, 2006
Noriaki Minakawa, Kazuyuki Kuramoto, Sadao Hikishima, Akira Matsuda   +3 more
openalex   +2 more sources

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

Oligonucleotide therapies for disorders of the nervous system

Nature Biotechnology, 2017
O. Khorkova, C. Wahlestedt
semanticscholar   +1 more source

8-Quinolinesulfonyl chloride as a coupling agent in oligonucleotide synthesis via phosphotriester approach

, 1978
Hiroshi Takaku, Masaastu Kato, Masatoshi Yoshida, Tsujiaki Hata   +3 more
openalex   +2 more sources

Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity

Advanced Science, EarlyView.
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee, Minjae Kim, Gha Yeon Park, Jubeen Yoon, Kunyoo Shin, Chang Ho Sohn, Myunghwan Choi   +6 more
wiley   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

BMX-001, a clinically relevant radioprotector, can reverse radiation-induced fibrosis when given three weeks after radiation, in part, by restoring methylation. [PDF]

Redox Biol
Myers MS, Kosmacek EA, Liew CS, Lushnikov AJ, Chatterjee A, Marky LA, Riethoven JM, Oberley-Deegan RE.   +7 more
europepmc   +1 more source