Results 201 to 210 of about 732,131 (343)

Harnessing oligonucleotide architecture for potent multivalent inhibition of human carbonic anhydrases. [PDF]

RSC Med Chem
Abbass EM, Ladu F, Mansot J, Noël M, Nocentini A, Sechi M, Supuran CT, Smietana M, Winum JY.   +8 more
europepmc   +1 more source

Oligonucleotide [PDF]

, 2020
openaire   +1 more source

A framework for oligonucleotide microarray preprocessing

Bioinform., 2010
B. Carvalho, R. Irizarry
semanticscholar   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Versatile introduction of multifunctional Michael-acceptor moieties on amino-oligonucleotides for bioconjugation purposes. [PDF]

Commun Chem
Meffert JH, Lopes M, Cadoni E, Bollmark M, Tedebark U, Madder A.   +5 more
europepmc   +1 more source

Characterization of the major altered leader sequence of late mRNA induced by SV40 deletion mutant d1-1811 [PDF]

, 1979
Haegeman, Guy, Iserentant, Dirk, Gheysen, Dirk, Fiers, Walter   +3 more
core   +2 more sources

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

, 1998
S. Der, Aimin Zhou, B. Williams, R. Silverman   +3 more
semanticscholar   +1 more source

Oligonucleotide-Peptide Complexes: Phase Control by Hybridization.

Journal of the American Chemical Society, 2018
J. Vieregg, Michael J Lueckheide, Amanda B. Marciel, Lorraine Leon, Alex J Bologna, Josean Reyes Rivera, M. Tirrell   +6 more
semanticscholar   +1 more source

G4‐Ligand‐Directed PROTACs Unveil DR1 as a Novel Ligand‐Co‐Binding G4‐Protein and Reshape G4‐Dependent Transcription

Advanced Science, EarlyView.
G4‐binding proteins (G4BPs) that specifically co‐bind G4s in the presence of small‐molecule ligands represent a critical but unexplored class of proteins. We introduce G4‐Ligand‐Directed PROTACs (G4L‐TACs), a chemical platform that couples G4 ligands (PDS) to E3 recruiters to selectively degrade these ligand‐co‐binding G4BPs.
Mao‐Lin Li, Shu‐Min Xu, Xin‐Chen Jiang, Le‐Tian Dai, Yu‐Tao Hu, Kai‐Bo Wang, Jia‐Heng Tan, Zhi‐Shu Huang, Shuo‐Bin Chen   +8 more
wiley   +1 more source

Human complement factor H [PDF]

, 1987
Dierich, Manfred P., Linke, Reinhold P., Schulz, T. F., Schwaeble, Wilhelm, Weiss, Elisabeth H., Zwirner, Jörg   +5 more
core   +1 more source