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A Convenient Fluorogenic Detection Strategy for Phosphorothioate Modification of DNA Through Photocatalytic Oligonucleotide-Templated Reaction. [PDF]

Biomolecules
Jing N, Qin Y, Fan X, Wang Q, Wang J, You F, Tang X.   +6 more
europepmc   +1 more source

Towards One-Step and Universal Synthesis of Hypermodified Uracil Nucleosides: acp³U and cmnm⁵U

Mejdr E, Heinickel L, Carell T, Mejdr I.
europepmc   +1 more source

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Oligonucleotide lipoplexes: the influence of oligonucleotide composition on complexation

Biochimica et Biophysica Acta (BBA) - General Subjects, 2001
Despite extensive investigations into oligonucleotide lipoplexes, virtually no work has addressed whether the physicochemical properties of these assemblies vary as a function of the constituent oligonucleotide (ODN) sequence and/or composition. The present study was aimed at answering this question.
Meidan, V.M., Glezer, J., Amariglio, N., Cohen, J.S., Barenholz, Y.   +4 more
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The Prebiotic Synthesis of Oligonucleotides

Origins of Life, 1974
This paper is primarily a review of recent developments in the abiotic synthesis of nucleotides, short chain oligonucleotides, and their mode of replication in solution. It also presents preliminary results from this laboratory on the prebiotic synthesis of thymidine oligodeoxynucleotides.
E. Stephen-Sherwood, J. Oró
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Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment

Current Medicinal Chemistry, 2005
In this account we summarise recent studies on oligonucleotides and oligonucleotide derivatives and their utilisation in antigene, antisense and decoy approaches, with particular attention to peptide nucleic acids, locked nucleic acids and oligonucleotide conjugates, the most promising compounds in this field.
DA ROS, TATIANA, SPALLUTO, GIAMPIERO, PRATO, MAURIZIO, SAISON BEHMOARAS T, BOUTORINE A, CACCIARI B.   +5 more
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Diagnosis with oligonucleotides

Clinics in Dermatology, 1991
Abstract Protein-based immunohistochemical techniques like immunoperoxidase methods are now routinely used in many diagnostic dermatopathology laboratories. This is possible because of the availability of antibodies that react with specific, diagnostically useful proteins and because there are simple but sensitive detection systems.
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Antisense Oligonucleotides

Nephron Experimental Nephrology, 1998
Antisense technology was developed to inhibit gene expression by utilizing an oligonucleotide complementary to the mRNA which encodes the target gene. There are a few possible mechanisms for the inhibitory effects of antisense oligonucleotides. Among them, degradation of mRNA by RNase H is considered to be the major mechanism of action for antisense ...
N, Kashihara, Y, Maeshima, H, Makino
openaire   +2 more sources