Results 311 to 320 of about 635,743 (331)
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Therapeutic Applications Of Oligonucleotides
Annual Review of Pharmacology and Toxicology, 1992This review focuses strictly on the pharmacodynamic considerations of the use of oligonucleotides designed to interact with nucleic acids as therapeutics. The objectives are to place oligonucleotide therapeutics in the context of modern drug discovery and development and to summarize recent progress.
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Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment
Current Medicinal Chemistry, 2005In this account we summarise recent studies on oligonucleotides and oligonucleotide derivatives and their utilisation in antigene, antisense and decoy approaches, with particular attention to peptide nucleic acids, locked nucleic acids and oligonucleotide conjugates, the most promising compounds in this field.
DA ROS, TATIANA +5 more
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Oligonucleotide Microarrays: Immobilization of Phosphorylated Oligonucleotides on Epoxylated Surface
Bioconjugate Chemistry, 2006A facile and efficient method for direct immobilization of phosphorylated oligonucleotides on an epoxy-activated glass surface is described. The new immobilization strategy has been analyzed for its performance in DNA microarray under both microwave and thermal conditions.
S, Mahajan, P, Kumar, K C, Gupta
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1993
Abstract 10.1 Single-crystal X-ray structure determination of oligonucleotides containing four or more bases Tables 10.1-10.5 list the principal references to structure determinations published between 1979 and mid-1989. There are three main families of double-helical oligonucleotide structures.
Olga Kennard +2 more
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Abstract 10.1 Single-crystal X-ray structure determination of oligonucleotides containing four or more bases Tables 10.1-10.5 list the principal references to structure determinations published between 1979 and mid-1989. There are three main families of double-helical oligonucleotide structures.
Olga Kennard +2 more
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Combinational synthesis of oligonucleotides and assembly fabrication of oligonucleotide array
Colloids and Surfaces B: Biointerfaces, 2005In this paper, a simple, reliable and flexible method, which integrated in situ synthesis with the spotting technique, was reported to fabricate oligonucleotide array. Different oligonucleotide sequences are synthesized on their relative code glass slides through combinational chemistry, thus the slides are broken into smaller pieces, in which the same
P F, Xiao +4 more
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Chromatography of oligonucleotides
Archives of Biochemistry and Biophysics, 1959M, STAEHELIN, E A, PETERSON, H A, SOBER
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