Results 111 to 120 of about 708,274 (274)
Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects
BMEMat, EarlyView.This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen +6 more
wiley +1 more source
Quality assessment for short oligonucleotide microarray data [PDF]
arXiv, 2007 Quality of microarray gene expression data has emerged as a new research topic. As in other areas, microarray quality is assessed by comparing suitable numerical summaries across microarrays, so that outliers and trends can be visualized, and poor quality arrays or variable quality sets of arrays can be identified.
arxiv
ChemBioChem, EarlyView.In this concept article, it is discussed how spatial control over the formation and movement of biomolecular condensates (BMCs) can be achieved and how this type of control can help in the reliable generation and study of BMCs. Spatial control over BMCs is crucial in vivo and therefore also desirable for in vitro studies in order to approach relevant ...
Alexander K. Buell
wiley +1 more source
Limit Theorems for Hybridization Reactions on Oligonucleotide Microarrays [PDF]
arXiv, 2008 We derive herein the limiting laws for certain stationary distributions of birth-and-death processes related to the classical model of chemical adsorption-desorption reactions due to Langmuir. The model has been recently considered in the context of a hybridization reaction on an oligonucleotide DNA microarray.
arxiv
Designing Enzymatic Reactivity with an Expanded Palette
ChemBioChem, EarlyView.Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley +1 more source
RPA: Probabilistic analysis of probe performance and robust summarization [PDF]
arXiv, 2011 Probe-level models have led to improved performance in microarray studies but the various sources of probe-level contamination are still poorly understood. Data-driven analysis of probe performance can be used to quantify the uncertainty in individual probes and to highlight the relative contribution of different noise sources.
arxiv
Catalysis in Chemical Modification of Proteins
ChemCatChem, Accepted Article.Advancement of catalytic transformations in traditional synthetic organic chemistry have made significant impacts on development of novel bioconjugation technologies. While a wide range of applications have become possible through catalytic protein bioconjugation approaches, there has been a lack of literature collectively reviewing advances of ...
Seiya Ishizawa +4 more
wiley +1 more source
A new formalism for calculation of the partition function of single stranded nucleic acids [PDF]
arXiv, 2005 A new formalism for calculation of the partition function of single stranded nucleic acids is presented. Secondary structures and the topology of structure elements are the level of resolution that is used. The folding model deals with matches, mismatches, symmetric and asymmetric interior loops, stacked pairs in loop and dangling end regions, multi ...
arxiv
Label‐Free Photonic Biosensors: Key Technologies for Precision Diagnostics
ChemistryEurope, EarlyView.Photonic biosensors are versatile technologies promising unique advantages to improve current diagnosis workflows. On‐going research is directed to systems integration and automation as well as enhancing assay performance. Advances in bioengineering, material sciences, and photonics engineering will be the key toward their eventual implementation as ...
Maria Soler, Laura M. Lechuga
wiley +1 more source
Mutation model for oligonucleotides fitting a Yule distribution [PDF]
arXiv, 2004 A spin chain, describing a nucleotides sequence, is identified by the labels of a vector state of an irreducible representation of U_q->0(sl2). A master equation for the distribution function is written, where the intensity of the one-spin flip is assumed to depend on the variation of the labels.
arxiv