Results 91 to 100 of about 23,719,178 (251)

Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication

Angewandte Chemie, EarlyView.
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero, Line Mørkholt Lund, Lasse Hyldgaard Klausen, Obinna Markraphael Ajunwa, Mingdong Dong, Rikke Louise Meyer, Victoria Birkedal, Kai Thormann   +7 more
wiley   +2 more sources

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

Molecular Cancer, 2006
Background Somatic mutations of mitochondrial DNA (mtDNA) are common in many human cancers. We have described an oligonucleotide microarray ("MitoChip") for rapid sequencing of the entire mitochondrial genome (Zhou et al, J Mol Diagn 2006), facilitating ...
Montgomery Elizabeth A, Eshleman James R, Lee Edward E, Canto Marcia, Wang Jean, Zhou Shaoyu, Sui Guoping, Sidransky David, Califano Joseph A, Maitra Anirban   +9 more
doaj   +1 more source

Oligonucleotide nomenclature and sequence.

, 2013
Oligonucleotide nomenclature and sequence.
Chunquan Cai (407557), Xianjun Gao (329570), Haifang Yin (378870), Hongjing Niu (407554), Qingsong Wang (407555), Limin Cao (407556), Gang Han (127634), Lu Yang (30847), Jan Weiler (30106)   +8 more
core   +1 more source

Multilocus sequence typing of Staphylococcus aureus with DNA array technology [PDF]

, 2003
A newly developed oligonucleotide array suited for multilocus sequence typing (MLST) of Staphylococcus aureus strains was analyzed with two strain collections in a two-center study.
Jay, C. (Corinne), Snijders, S.V. (Susan), Troesch, A, Leeuwen, Willem, Enright, MC, Troesch, A. (Alain), Verbrugh, H.A. (Henri), Belkum, Alex, Lacroix, B, Belkum, A.F. (Alex) van, Snijders, Susan, Enright, M.C. (Mark), Leeuwen, W.B. (Willem) van, Lacroix, B. (Bruno), Jay, C, Durin, N. (Nathalia), Verbrugh, Henri, Durin, N   +17 more
core   +1 more source

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Biotin‐ and Chloroalkane‐Modified Nucleotides for Dual Display of Proteins on DNA Through Streptavidin and Halotag Binding

Angewandte Chemie, EarlyView.
Modified 2’‐deoxy‐7‐deazaadenosine bearing a chlorohexyl moiety and 2’‐deoxycytidine nucleotides bearing biotin were used in the enzymatic synthesis of dually modified dsDNAs that served as scaffolds for display of halotag and monomeric streptavidin proteins.
Giammarco Liuni, Lenka Poštová Slavětínská, Miroslav Hájek, Veronika Raindlová, Michal Hocek   +4 more
wiley   +2 more sources

MIMAS 3.0 is a Multiomics Information Management and Annotation System

BMC Bioinformatics, 2009
Background DNA sequence integrity, mRNA concentrations and protein-DNA interactions have been subject to genome-wide analyses based on microarrays with ever increasing efficiency and reliability over the past fifteen years.
Rougemont Jacques, Collin Olivier, Xenarios Ioannis, Liechti Robin, Hermida Leandro, Gattiker Alexandre, Primig Michael   +6 more
doaj   +1 more source

Whole genome comparative studies between chicken and turkey and their implications for avian genome evolution [PDF]

, 2008
BACKGROUND: Comparative genomics is a powerful means of establishing inter-specific relationships between gene function/location and allows insight into genomic rearrangements, conservation and evolutionary phylogeny.
Griffin, D.K., Gaginskaya, E., Robertson, L. B., Völker Martin, Masabanda, Julio S., Burt, D.W., Valérie Fillon, Svetlana Deryusheva, Robertson Lindsay B, Griffin Darren K, Fillon, V., Masabanda, J. S., Martin Völker, Richard Talbot, Crooijmans, Richard P.M.A., Darren K Griffin, Gaginskaya, Elena, Vignal Alain, Martien AM Groenen, Crooijmans, Richard P. M. A., Dave W Burt, Groenen, M.A.M., Burt Dave W, Robertson, L.B., Griffin, D. K., Burt, D. W., Helen G Tempest, Carre, Wilfrid, Vignal, Alain, Julio S Masabanda, Crooijmans, R.P.M.A., Burt, Dave W, Tempest, H.G., Groenen, Martien A. M., Griffin, Darren K., Deryusheva, Svetlana, Waddington David, Talbot, Richard, Waddington, D., Robertson, Lindsay B., Robertson, Lindsay, Carré Wilfrid, Masabanda, Julio S, Groenen, Martien AM, Tempest, Helen G., Gaginskaya Elena, Fillon Valérie, Burt, Dave W., Waddington, David, Tempest, H. G., Groenen Martien AM, Fillon, Valerie, Lindsay B Robertson, Talbot Richard, Crooijmans, R. P., Deryusheva, S., Elena Gaginskaya, Masabanda Julio S, Tempest Helen G, Volker, Martin, Crooijmans, Richard PMA, Groenen, M. A., David Waddington, Deryusheva Svetlana, Talbot, R., Wilfrid Carré, Richard PMA Crooijmans, Masabanda, J.S., Vignal, A., Alain Vignal, Burt, David W., Crooijmans Richard PMA, Volker, M., Carre, W.   +73 more
core   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Genome-wide mapping of ORC and Mcm2p binding sites on tiling arrays and identification of essential ARS consensus sequences in S. cerevisiae

BMC Genomics, 2006
Background Eukaryotic replication origins exhibit different initiation efficiencies and activation times within S-phase. Although local chromatin structure and function influences origin activity, the exact mechanisms remain poorly understood.
Aparicio Oscar M, Aparicio Jennifer G, Xu Weihong, Tavaré Simon   +3 more
doaj   +1 more source