Results 141 to 150 of about 79,402 (200)

One-pot CRISPR-based point of care platform for rapid, specific and sensitive detection of HPV 16 without pre-amplification. [PDF]

Microsyst Nanoeng
Chen Y, Chen Y, Zhang C, Cai Y, Zeng Z, Reboud J, Cooper JM, Shan H, Wang Y, Xu G.   +9 more
europepmc   +1 more source

Ions as Architects of DNA Nanostructures: Mechanisms, Simulations, and Technological Frontiers

Small Structures, Volume 7, Issue 3, March 2026.
Ions are not merely passive electrolytes but active regulators of DNA nanostructures. This review shows how ion valence, hydration, and specificity govern electrostatic screening, correlation, and confinement, enabling DNA origami, metallized DNA, nanopores, hydrogels, DNAzymes, molecular machines, and energy devices through integrated experimental and
Sergiy Perepelytsya, Dmytro Piatnytskyi, Tetiana Bubon, Narcis Cibotariu, Aatto Laaksonen, Francesca Mocci   +5 more
wiley   +1 more source

Batch optimization for balanced binary sequences and DNA sequences. [PDF]

BMC Bioinformatics
Ma Y.
europepmc   +1 more source

Skim‐sequencing for genomic selection in wheat: a comparison of marker platforms

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract The promise of genomics‐assisted breeding relies on efficient, affordable, and abundant molecular markers. Leveraging modern sequencing technology, commercial laboratory products, and open‐source software, we demonstrate how ultra‐low whole‐genome sequencing coverage (skim‐seq, 0.05–0.10x) can be a viable marker platform. The direct generation
Jared L. Crain, José Crossa, Lee DeHaan, Susanne Dreisigacker, Jesse Poland, Ravi P. Singh, Paolo Vitale   +6 more
wiley   +1 more source

Automated high-throughput selection of DNA aptamers using a common optical next-generation sequencer. [PDF]

Nucleic Acids Res
Drees A, Ahlers C, Kehrer T, Ehmke N, Grün AFR, Uetrecht C, Ignatova Z, Schumacher U, Fischer M.   +8 more
europepmc   +1 more source

Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists

WIREs RNA, Volume 17, Issue 2, March/April 2026.
U‐indel RNA editing targets mRNA:gRNA duplexes through three key complexes that collectively govern assembly, specificity, catalysis, and developmental regulation. Modern tools, including artificial intelligence, analyze the organization, dynamics, and evolution of the remarkable holo‐editosome, opening new avenues in RNA biology and therapy.
Suzanne M. McDermott, Julius Lukeš, Laurie K. Read, Reza Salavati, Achim Schnaufer, Sara L. Zimmer, Jason Carnes, Alasdair Ivens, Naghmeh Poorinmohammad, Nicholas J. Savill, Dave Speijer, Ken Stuart, Kristína Záhonová, Poorya Mirzavand Borujeni, Zihao Chen, Cody Goode, Sunil Kumar Sharma, Lars O’Hara, Jorge Cruz‐Reyes   +18 more
wiley   +1 more source

Analysis of copy number variations and candidate genes in recurrent pregnancy loss. [PDF]

PeerJ
Wang L, Yang L, Li S, Liu X, Tang P.
europepmc   +1 more source

Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomous effects in the B‐cell compartment

The FEBS Journal, Volume 293, Issue 5, Page 1459-1477, March 2026.
Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver, Rachael Riley Denbrock, Cindy Carolina Martines, Alessandro Didonna   +3 more
wiley   +1 more source

Ion Mobility Gas-Phase Separation Enhances Top-Down Mass Spectrometry of Heavily Modified Guide RNA. [PDF]

Anal Chem
Macias LA, Lowther J, Tillotson EL, Rohde E, Madsen JA.   +4 more
europepmc   +1 more source

A signaling pathway mediating abscisic acid‐induced jasmonic acid biosynthesis during strawberry ripening

Journal of Integrative Plant Biology, Volume 68, Issue 3, Page 777-792, March 2026.
During strawberry ripening, abscisic acid signaling activates SnRK2.6, which phosphorylates and degrades the JAZ12 repressor. This releases the MYC2 transcription factor, directly activating jasmonic acid biosynthesis genes. The resulting jasmonic acid accumulation drives aroma production, thereby coupling ripening with scent formation through this ...
Kenan Jia, Baozhen Zeng, Zhengrong Dai, Xiaoming Zhang, Jing Wang, Chuanbao Wu, Chen Feng, Guohua Yan, Kaichun Zhang, Xuwei Duan, Wei Wang   +10 more
wiley   +1 more source